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Zocht je misschien: indeed?

Reliability of a software program to analyze endothelial function.

Steven Onkelinx (Begeleider); Katerina Chamatila (Student)

Background: Endothelial dysfunction is a marker of early stages of atherosclerosis and in general of cardiovascular disease. Assessing the endothelium can be achieved non-invasively, using the flow-mediated dilatation technique. Method: For the experiment 21 patients with an inactive cardiovascular …

2013GezondheidBachelor

Resonance enhanced laser-induced breakdown spectroscopy

Daniel Bouman (Student); C.A. Swarts (Begeleider)

Resonance-enhanced laser-induced breakdown spectroscopy was used to increase the elemental sensitivity of laser-induced breakdown spectroscopy. In resonance-enhanced laser-induced breakdown spectroscopy, two lasers are used. The first laser creates a plasma, and the second laser re excites the most …

2013TechniekBachelor

Prolonged electrical stimulation-induced gluteal and hamstring muscle activation and sitting pressure in spinal cord injury: Effect of duty cycle

MSc Karin J.A. Legemate; MD Christof A. J. Smit; MSc Anja de Koning (Docent); PhD Sonja de Groot; MD, PhD Janneke M. Stolwijk-Swuste; PhD Thomas W.H. Janssen

Abstract—Pressure ulcers (PUs) are highly prevalent in people with spinal cord injury (SCI). Electrical stimulation (ES) activates muscles and might reduce risk factors. Our objectives were to study and compare the effects of two duty cycles during 3 h of ES-induced gluteal and hamstring activation on …

2013AlgemeenArtikel

The effect of Porphyromonas gingivalis lipopolysaccharide on pregnancy in the rat

Kunnen, Alina; van Pampus, M.G.; van der Schans, Cees (Healthy Ageing, Allied Health Care And Nursing); Abbas, F.; Faas, M.M.; Aarnoudse, Jan G

OBJECTIVE: Periodontitis, mostly associated with Porphyromonas gingivalis, has frequently been related to adverse pregnancy outcomes. We therefore investigated whether lipopolysaccharides of P. gingivalis (Pg-LPS) induced pregnancy complications in the rat. METHODS: Experiment 1: pregnant rats (day 14) …

2013AlgemeenArtikel

Long term effects of Constraint Induced Movement Therapy on the functional recovery of upper limb paresis in stroke patients.

Roderick Wondergem (Begeleider); Hortensia Luxem (Student)

Background: Stroke is one of the leading causes of illnesses, affecting approximately 15 million people worldwide every year. A large amount of stroke patients are left with upper extremity paresis in the long term. Several studies have been made on the effect of Constraint Induced Movement Therapy …

2013GezondheidBachelor

Constraint Induced Movement Therapy : use it and improve it, or lose it?

Lisa Baart

Achtergrond en doel: Volgens recent onderzoek zijn CIMT en mCIMT mogelijk goede therapieën om de hand- en armfunctie van een CVA patiënt te verbeteren. Het doel van deze literatuurstudie is om het effect van CIMT en mCIMT te vergelijken met het effect van conventionele therapieën. Methode: Zes artikelen …

2013GezondheidBachelor

Identification of biomarkers to detect residual pertussis toxin using microarray analysis of dendritic cells

R.J. Vandebriel; Saertje Verkoeijen (Lid Lectoraat); A.M. Akkermans; Stefan Vaessen (Lid Lectoraat); M.W.P. Bruysters; J.L.A. Pennings; R. Bos; Cyrille Krul (Lector)

tIn this study we aimed to identify genes that are responsive to pertussis toxin (PTx) and might eventu-ally be used as biological markers in a testing strategy to detect residual PTx in vaccines. By microarrayanalysis we screened six human cell types (bronchial epithelial cell line BEAS-2B, fetal lung …

2013Natuur & LandbouwArtikel

Org 214007-0

van Lierop, Marie-José C; Alkema, Wynand (Data Science For Life Science & Health); Laskewitz, Anke J; Dijkema, Rein; van der Maaden, Hans M; Smit, Martin J; Plate, Ralf; Conti, Paolo G M; Jans, Christan G J M; Timmers, C Marco; van Boeckel, Constant A A; Lusher, Scott J; McGuire, Ross; van Schaik, Rene C; de Vlieg, Jacob; Smeets, Ruben L; Hofstra, Claudia L; Boots, Annemieke M H; van Duin, Marcel; Ingelse, Benno A; Schoonen, Willem G E J; Grefhorst, Aldo; van Dijk, Theo H; Kuipers, Folkert; Dokter, Wim H A

Glucocorticoids (GCs) such as prednisolone are potent immunosuppressive drugs but suffer from severe adverse effects, including the induction of insulin resistance. Therefore, development of so-called Selective Glucocorticoid Receptor Modulators (SGRM) is highly desirable. Here we describe a non-steroidal …

2012-11-12AlgemeenArtikel

The Pirate group intervention protocol description and a case report of a modified constraint-induced movement therapy combined with bimanual training for young children with unilateral spastic cerebral palsy

Aarts, Pauline B.; van Hartingsveldt, Margo (Faculteit Gezondheid); Anderson, Patricia G.; van den Tillaar, Ingrid; van der Burg, Jan; Geurts, Alexander C.

The purpose of this article was to describe a child-friendly modified constraint-induced movement therapy protocol that is combined with goal-directed task-specific bimanual training (mCIMT-BiT). This detailed description elucidates the approach and supports various research reports. This protocol is …

2012-06AlgemeenArtikel

Molecular pathway profiling of T lymphocyte signal transduction pathways; Th1 and Th2 genomic fingerprints are defined by TCR and CD28-mediated signaling

Smeets, Ruben L; Fleuren, Wilco W M; He, Xuehui; Vink, Paul M; Wijnands, Frank; Gorecka, Monika; Klop, Henri; Bauerschmidt, Sussane; Garritsen, Anja; Koenen, Hans J P M; Joosten, Irma; Boots, Annemieke M H; Alkema, Wynand (Data Science For Life Science & Health)

BACKGROUND: T lymphocytes are orchestrators of adaptive immunity. Naïve T cells may differentiate into Th1, Th2, Th17 or iTreg phenotypes, depending on environmental co-stimulatory signals. To identify genes and pathways involved in differentiation of Jurkat T cells towards Th1 and Th2 subtypes we performed …

2012-03-14AlgemeenArtikel

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