This paper describes the development of one solid phase extraction method for a wide group of pharmaceutical and industrial compounds in wastewater that is analyzed with two LC-MS/MS methods.

Alzheimer’s disease is the leading cause of dementia affecting over 46 million worldwide, yet contemporary medication is unable to prevent or slow its neurodegeneration. Recently, fucosterol and saringosterol, two phytosterols from brown macroalgae, have emerged as possible mediators of the disease. …

Bij een incident kunnen stoffen vrijkomen die mens, milieu en dier mogelijk in gevaar kunnen brengen. Hiervoor is het noodzakelijk om snel informatie te verkrijgen van de vrijgekomen stoffen. De informatie kan worden gehaald uit analyseresultaten van de op de locatie verkregen monsters. Hedendaags wordt …

Bryophytes are small, haploid, non-vascular plants, which can be divided in three distinct phyla; the mosses (Musci), the liverworts (Hepaticae) and the hornworts (Anthocerotae) (Gradstein & Melick, 1996), (Touw, Kruijer, & Stech, 2016). They are valuable indicators of environmental chance, due to the …

Recent research has shown that many chloroplast markers commonly used for the identification of species in land plants are not useful in the moss genus Campylopus. The only known suitable marker in Campylopus is the nuclear ribosomal ITS1-5.8S-ITS2 region. However, evolutionary patterns of this region …

For research to the composition of oxylipids in human plasma and tissue it was necessary to have an analytical method that can measure these lipids on very low concentrations. In this bachelor thesis the development of a LC-MS method will be discussed.

Als iemand wordt blootgesteld aan een zenuwgas (OP), blokkeert dit zenuwgas de werking van het enzym acetylcholinesterase (AChE). AChE heeft als functie dat het de neurotransmitter acetylcholine (ACh) afbreekt. Als ACh niet afgebroken wordt raken de spieren in het lichaam overgestimuleerd, waardoor het …

In this study, various extraction methods were compared based on their ability to extract both free amino acids, and free 5’-monophosphate nucleotides from the seaweed Saccharina latissima. Based on the results, extraction at room temperature with Milli-Q over 24 hours was chosen as the method of choice, …

Relatively new products which are mostly marketed by online communities and online influencers as healthy or having therapeutic effects are being sold across Europe and United States, online or local drugstores, without ensuring that these products go through any quality analysis. This introduces a threat …

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