Diabetes remains a major risk for atherosclerotic-cardiovascular disease (CVD). While many mechanisms have been explored, the full extent of how diabetes promotes CVD remains unknown. An emerging area in diabetes is the influence of epigenetic regulation of gene expression. Diabetes has been shown to …

Meer dan 90% van mensen met dementie vertoont symptomen van psychisch lijden zoals depressie, angst of apathie. Onderzoek liet zien dat er vaak onvolledig of onjuist wordt omgegaan met probleemgedrag, zelfs na invoering van de richtlijn ‘Probleemgedrag bij mensen met dementie’ in 2018. In de STIP-Methode …

Als in het voorjaar de watertemperatuur stijgt, maken oesters zich klaar voor de voortplanting. Dit is het startpunt van nieuwe oesters. Zodra de bevruchting van eicellen plaats heeft gevonden, worden er oesterlarven gevormd. Maar wanneer zijn deze oesterlarven waarneembaar in de waterkolom en komen …

Background the efficacy and outcomes of geriatric rehabilitation (GR) have previously been investigated. However, a systematic synthesis of the aspects that are important to patients regarding the quality of GR does not exist. Objective the aim of this scoping review was to systematically synthesise …

Introduction Radical cystectomy (RC) is the standard treatment for patients with non-metastatic muscle-invasive bladder cancer, as well as for patients with therapy refractory high-risk non-muscle invasive bladder cancer. However, 50–65% of patients undergoing RC experience perioperative complications. …

Abstract Introduction: The factors influencing patients' motivation for undergoing electrocon vulsive therapy (ECT) have not yet been subjected to a thorough study. Knowledge of these factors could improve the quality of care for patients with depression recom mended to have ECT. Aim: To identify the …

Non-invasive, rapid, on-site detection and identification of body fluids is highly desired in forensic investigations. The use of fluorescence-based methods for body fluid identification, have so far remain relatively unexplored. As such, the fluorescent properties of semen, serum, urine, saliva and …

Anthropogenic changes to estuaries, usually highly productive systems, may result in increased turbidity levels, suppress pelagic primary production and negatively affect ecosystem functions. The Ems-Dollard estuary, enclosed between the Netherlands and Germany, is such an estuary with a long history …

Abstract Background Smoking among people with severe mental illness (SMI) is highly prevalent and strongly associated with poor physical health. Currently, evidence-based smoking cessation interventions are scarce and need to be inte grated into current mental health care treatment guidelines and clinical …

Het afgelopen decennium is het aantal masteropgeleiden in het onderwijs, mede door diverse beleidsmaatregelen gericht op versterking van de onderwijskwaliteit, sterk toegenomen. In die periode is de vraag gerezen hoe deze masteropgeleiden daadwerkelijk in te zetten zijn ten gunste van de onderwijskwaliteit. …