From the article: "To enable selection of novel chemicals for new processes, there is a recognized need for alternative toxicity screening assays to assess potential risks to man and the environment. For human health hazard assessment these screening assays need to be translational to humans, have …

Accurate assessment of TP53 gene status in sporadic tumors and in the germline of individuals at high risk of cancer due to Li–Fraumeni Syndrome (LFS) has important clinical implications for diagnosis, surveillance, and therapy. Genomic data from more than 20,000 cancer genomes provide a wealth of information …

Climate change is a global issue, and it may result in consequences. In order to solve climate change, actors gather at the UN Climate Change Conference to conclude an agreement. However, sometimes reaching an agreement cannot be successful. Compared to animals, it can be said that animals make accurate …

The target article describes an interesting study, which provides some challenging findings regarding athletes' pathway to excellence. The suggested links between critical life events, need for success, personal characteristics, and eventual performance level make sense from a psychodynamic perspective. …

This report provides an overview of a literature study focused the conflict between polar bears (Ursus maritimus) and humans and gives an overview of measures that could reduce or avoid human-polar bear conflict (HPBC). The goal of this study is to provide an insight into which measures are most successful …

From the article: Abstract Sub-chronic toxicity studies of 163 non-genotoxic chemicals were evaluated in order to predict the tumour outcome of 24-month rat carcinogenicity studies obtained from the EFSA and ToxRef databases. Hundred eleven of the 148 chemicals that did not induce putative preneoplastic …

Background In 2007, routine hepatitis C virus (HCV) antibody testing was introduced for men who have sex with men (MSM) with a human immunodeficiency virus (HIV)-positive or unknown status attending a Dutch sexually transmitted infection (STI) outpatient clinic. We evaluated whether this screening resulted …

Presentation, held at the 24th IAPS Conference. In accordance with the IAPS mission (www.iaps-association.org), the conference did address the study of the interrelations between the social, the built and the natural environment, and the impacts on them. The conference theme turns the spotlight on to …

We set out to bring into being a Creative Methods issue to inform and support researchers, practitioners, educators, and those they serve. We did so with what William Blake called “a firm persuasion” (Whyte, 2001, p. 3), and in the process of expanding the vidence-base for creative methods in guidance …

From the article: "The term Internet of Things (IoT) is used for situations where one or more devices are connected to a network or possibly the Internet. Most studies focus on the possibilities that arise when a device is capable to share its data with other devices or humans. In this study, the focus …