This graduation report describes a research project at the research group metabolomics of the Leiden center of Applied Biosciences (LCAB). The aim of this project was to develop a GC-MS method for the identification of red swamp crayfish pheromones (Procambarus clarkii). Once this method has been developed, …

The massive die-off of the herbivorous sea urchin Diadema antillarum in 1983 and 1984 resulted in phase shifts on Caribbean coral reefs, where macroalgae replaced coral as the most dominant benthic group. Since then, D. antillarum recovery has been slow to non-existent on most reefs. Studying settlement …

INTRODUCTION: With the introduction of digital radiography, the feedback between image quality and over-exposure has been partly lost which in some cases has led to a steady increase in dose. Over the years the introduction of exposure index (EI) has been used to resolve this phenomenon referred to as …

The World Health Organization engages cities and communities all over the world in becoming age-friendly. There is a need for assessing the age-friendliness of cities and communities by means of a transparently constructed and validated tool which measures the construct as a whole. The aim of this study …

BACKGROUND: The original Rainbow Model of Integrated Care Measurement Tool (RMIC-MT) is based on the Rainbow Model of Integrated Care (RMIC), which provides a comprehensive theoretical framework for integrated care. To translate and adapt the original care provider version of the RMIC-MT and evaluate …

In this research several methods were developed and validated using the Supermini 200 wavelength dispersive X-ray fluorescence spectrometer. A multielement was calibrated containing 26 elements and corrected for interference according to the de Jongh algorithm. The limits of detection and quantification …

This research is to investigate to what extend the NIOSH-7605 and ISO-16740 methods can be used to determine insoluble hexavalent chromium in air. The methods were tested and optimized on the extraction and sample preparation steps. After optimization the methods were validation on limit of detection …

An attempt was made to develop a method for the determination of volatile organic compounds (VOCs) in air by gas chromatography mass spectrometry (GC-MS) analysis and chemical sample desorption of the 3M 3500 passive diffusion sampler. The method included a complex mixture of 205 polar and non-polar …

In dit onderzoek zijn recente ontwikkelingen in Machine Learning (ML) en Deep Learning (DL) met betrekking tot borst-, fibroglandulair (FG)- en tumorweefselsegmentatie in MRI-mammografie in kaart gebracht, de prestaties van deze segmentatiesystemen zijn vergeleken en als laatste worden toekomst toepassingsmogelijkheden …