Patients suffering from bacterial bloodstream infections have an increased risk of developing systematic inflammatory response syndrome (SIRS), which can result in rapid deterioration of the patients’ health. Diagnostic methods for bacterial identification and antimicrobial susceptibility tests are time-consuming. …

Card sort studies can facilitate developers to create an information structure for their website or application. In addition, this human-centered design method provides researchers with insights into the target group’s mental models regarding the information domain under study. In this method, participants …

Abstract Background. Fever in children is common and mostly caused by self-limiting infections. However, parents of febrile children often consult in general practice, in particular during out-of-hours care. To improve management, it is important to understand experiences of GPs managing these consultations. Objective. …

The increase of antibiotic resistance worldwide, rising numbers of deaths and costs associated with this, and the fact that hardly any new antimicrobial drugs have been developed during the last decade have increased the interest in Complementary and Alternative Medicine (CAM) therapeutic interventions, …

Waterborne diseases are posing a constant threat for people. In developing countries there is a lack of microbiologically safe drinking water and in the developed countries there are occasional waterborne disease outbreaks. These diseases are caused by bacteria or parasites which can be found in various …

Children with acute respiratory or ear infections (RTI/OM) are often unnecessarily prescribed antibiotics. Antibiotic resistance is a major public health problem and antibiotic prescription for RTI/OM should be reduced. Anthroposophic treatment of RTI/OM includes anthroposophic medications, nonmedication …

The amount of used antibiotics is a large problem concerning human health. More and more resistance has occurred during the last years. The Dutch government has announced lowering of used antibiotics in the Netherlands has to be reached. The amount of used antibiotics can be described in several ways. …

Penicillin acylase (PA) from Escherichia coli can catalyze the coupling of an acyl group to penicillin- and cephalosporin-derived beta-lactam nuclei, a conversion that can be used for the industrial synthesis of beta-lactam antibiotics. The modest synthetic properties of the wild-type enzyme make it …