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Zocht je misschien: biomarkers?

State of the art: the role of citrulline as biomarker in patients with chemotherapy- or graft-versus-host-disease-induced mucositis

I.M. Dekker; H Bruggink; Barbara van der Meij; N. Wierdsma

Purpose of review Serum or plasma citrulline levels are used as biomarker for a broad spectrum of intestinal functions. During high-dose chemotherapy, citrulline levels are decreased due to mucositis, a common side effect of chemotherapy. This may decrease intestinal function and result in diarrhea. …

2021AlgemeenArtikel

Changes in inflammation and musculoskeletal tissue-derived biomarker serum levels in response to high- and low-intensity resistance training in individuals with knee osteoarthritis

Jansen, N.E.; Engstrøm, A.; Thudium, C.S.; Bay-Jensen, A-C.; de Zwart, A.H.; Dekker, J.; Lems, W.F.; Gerritsen, M.; van Spil, W.E.; Jaspers, R.T.; Turkstra, F.; van der Leeden, M.; van der Esch, M. (Lectoraat Interdisciplinaire Zorg Voor Chronische Gewrichtsaandoeningen)

Purpose: Exercise therapy with a focus on muscle strengthening has proven to be effective for the management of knee osteoarthritis (OA). Yet it is not known whether high-intensity resistance training (RT) is more effective in improving upper leg muscle strength and physical performance than low-intensity …

2020-04AlgemeenArtikel

Associations Between Nutrient Intake and Corresponding Nutritional Biomarker Levels in Blood in a Memory Clinic Cohort: The NUDAD Project

F.A. de Leeuw; O. van de Rest; A.S. Doorduijn; J.L.P. Fieldhouse; Marian de van der Schueren; M. Visser; E.G.H.M. van den Heuvel; P. Scheltens; C.E. Teunissen; M.I. Kester; W.M. van der Flier

2020AlgemeenArtikel

Advanced glycation end-products are associated with physical activity and physical functioning in the older population

Drenth, Hans; Zuidema, Sytse U; Krijnen, Wim P (Statistical Techniques For Applied Research); Bautmans, Ivan; Smit, Andries J; Schans, Cees van der (Healthy Ageing, Allied Health Care And Nursing); Hobbelen, Hans (Ageing And Allied Health Care)

Background: Decline in physical activity and functioning is commonly observed in the older population and might be associated with biomarkers such as Advanced Glycation End-products (AGEs). AGEs contribute to age-related decline in the function of cells and tissues in normal aging and have been found …

2018-10-08AlgemeenArtikel

The contribution of advanced glycation end product (AGE) accumulation to the decline in motor function

Drenth, Hans; Zuidema, Sytse; Bunt, Steven; Bautmans, Ivan; van der Schans, Cees (Healthy Ageing, Allied Health Care And Nursing); Hobbelen, Hans (Ageing And Allied Health Care)

Diminishing motor function is commonly observed in the elderly population and is associated with a wide range of adverse health consequences. Advanced Glycation End products (AGE’s) may contribute to age-related decline in the function of cells and tissues in normal ageing. Although the negative effect …

2016AlgemeenArtikel

Identification of new biomarker candidates for glucocorticoid induced insulin resistance using literature mining

Fleuren, Wilco WM; Toonen, Erik JM; Verhoeven, Stefan; Frijters, Raoul; Hulsen, Tim; Rullmann, Ton; van Schaik, René; de Vlieg, Jacob; Alkema, Wynand (Data Science For Life Science & Health)

Background: Glucocorticoids are potent anti-inflammatory agents used for the treatment of diseases such as rheumatoid arthritis, asthma, inflammatory bowel disease and psoriasis. Unfortunately, usage is limited because of metabolic side-effects, e.g. insulin resistance, glucose intolerance and diabetes. …

2013-02-04AlgemeenArtikel

Identification of biomarkers to detect residual pertussis toxin using microarray analysis of dendritic cells

R.J. Vandebriel; Saertje Verkoeijen (Lid Lectoraat); A.M. Akkermans; Stefan Vaessen (Lid Lectoraat); M.W.P. Bruysters; J.L.A. Pennings; R. Bos; Cyrille Krul (Lector)

tIn this study we aimed to identify genes that are responsive to pertussis toxin (PTx) and might eventu-ally be used as biological markers in a testing strategy to detect residual PTx in vaccines. By microarrayanalysis we screened six human cell types (bronchial epithelial cell line BEAS-2B, fetal lung …

2013Natuur & LandbouwArtikel

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