Achtergrond: Patiënten die een orgaantransplantatie ondergaan hebben, zullen hun leven lang immunosuppressiva moeten slikken. Bij deze patiëntengroep ontwikkelen zich vaak maligne huidaandoeningen (NMSC), voornamelijk plaveiselcelcarcinomen. Doelstelling: De doelstelling van het onderzoek is het weergeven …

Background: Drug resistance is a major problem in ovarian cancer. Triggering apoptosis using death ligands such as tumour necrosis factor-related apoptosis inducing ligand (TRAIL) might overcome chemoresistance. Methods: We investigated whether acquired cisplatin resistance affects sensitivity to recombinant …

In this paper, we explore the desires that play a role at the palliative stage and relate them to various approaches to patient autonomy. What attitude can physicians and other caregivers take to the desires of patients at the palliative stage? We examine this question by introducing five physicians …

An ELISA was set up using polyvinylchloride microtiter plates coated with rabbit anti-UK IgG's and affino-purified goat anti-UK IgG's as second antibody. Detection occurred with rabbit anti-goat IgG antibodies conjugated with alkaline phosphatase. The assay is specific for urokinase (UK) with a detection …