BACKGROUND: A stratified approach to exercise therapy may yield superior clinical and economic outcomes, given the large heterogeneity of individuals with knee osteoarthritis (OA). OBJECTIVE: To evaluate the cost-effectiveness during a 12-month follow-up of a model of stratified exercise therapy compared …

Doel. Dit onderzoek heeft als doel manieren te vinden om te bestuderen hoe verstandelijk gehandicapten met uitdagend gedrag omgaan met de ruimte, zonder hun dagelijks leven te beïnvloeden. Achtergrond. Onderzoek naar ruimte dat beter aansluit bij de behoeften van deze personen is een uitdaging om uit …

STUDY DESIGN: Cross-sectional study. OBJECTIVES: This study: (1) investigated the accuracy of bioelectrical impedance analysis (BIA) and skinfold thickness relative to dual-energy X-ray absorptiometry (DXA) in the assessment of body composition in people with spinal cord injury (SCI), and whether sex …

Problem-solving tasks form an important part of (higher education) curricula, especially in STEM-domains. For learners with little or no prior knowledge (novices), an effective way to learn new problem-solving tasks is by studying examples. These can be written out step-by-step solution procedures of …

Nowadays, students often practice problem-solving skills in online learning environments with the help of examples and problems. This requires them to self-regulate their learning. It is questionable how novices self-regulate their learning from examples and problems and whether they need support. The …

Organizations collect a vast amount of data of different types, from various sources, and through different channels. Primarily, these data are used by these organizations to facilitate their core business processes. However, today we witness a growing tendency to use these data for other purposes than …

Background: Previous studies found that 40-60% of the sarcoidosis patients suffer from small fiber neuropathy (SFN), substantially affecting quality of life. SFN is difficult to diagnose, as a gold standard is still lacking. The need for an easily administered screening instrument to identify sarcoidosis-associated …

Due to the many potential applications of Big Data, the expectations are high. However, there are some fundamental objections on the straightforward use of Big Data outcomes. In this paper, we take a philosophical view on the Big Data approach and discuss these objections. Formally, Big Data induces …

OBJECTIVE: We investigated smoking cessation rates in coronary heart disease (CHD) patients throughout Europe; current and as compared to earlier EUROASPIRE surveys, and we studied characteristics of successful quitters. METHODS: Analyses were done on 7998 patients from the EUROASPIRE-IV survey admitted …

The critical care community still has mixed feelings when considering the optimal nutrition of intensive care unit (ICU) patients, which is understandable as randomized controlled trials have not been very helpful in improving clinical practice. There have been no randomized controlled trials (RCTs) …