Respiratory syncytial virus (RSV) is a leading cause of acute lower respiratory tract infections (LRTI) in infants, and toddlers and vaccines are not yet available. A pediatric RSV vaccine (ChAd155-RSV) is being developed to protect infants against RSV disease. The ChAd155-RSV vaccine consists of a recombinant …

BACKGROUND: Since the benefit-harm balance of adding inhaled corticosteroids to long-acting β2-agonists (LABA) and long-acting muscarinic antagonists (LAMA) for patients with chronic obstructive pulmonary disease is unclear, we evaluated this addition for a range of patient profiles. METHODS: Analyses …

Lower cardiorespiratory fitness (CRF) and physical activity (PA) associate with higher cardiovascular disease (CVD) risk, but the relationship between CRF and PA in people who have rheumatoid arthritis (RA) at an increased CVD risk (CVD-RA) is not known. The objectives of this study were to determine …

Objective The purpose of this study was to investigate the relationship between body mass index (BMI) class and physical activity and sedentary behavior in patients with acute coronary syndrome (ACS) during cardiac rehabilitation (CR). Methods This study was a secondary analysis of the OPTICARE trial. …

This research paper is about optimizing open-world museum applications and maximizing their efficiency on low-end devices. The paper is commissioned by a gaming company Tag of Joy, to streamline the onboarding of junior artists by creating a game optimization guide that contains information about the …

Many technological innovations – the internet, social media, challenges via TikTok, etc. – influence development at least as radically as 'invented ' interventions, such as behavioural therapy or EMDR. In contrast to therapeutic interventions, however, this is often not or hardly thought about and …

Trust between providers and consumers in the sharing economy are crucial to complete transactions successfully. From a consumer's perspective, a provider's profile is an important source of information for judging trustworthiness, because it contains multiple trust cues. However, the effect of a provider's …

Pressure on healthcare The Netherlands is an aging country. According to the Dutch Bureau for Economic Policy Analysis (CPB), the aging of the population will become evident in the next government’s term of office, i.e. 2022–2025, alongside an increase of healthcare costs with an annual average of 2.7% …

Purpose: The purpose of this study was to validate optimized algorithm parameter settings for step count and physical behavior for a pocket worn activity tracker in older adults during ADL. Secondly, for a more relevant interpretation of the results, the performance of the optimized algorithm was compared …

With recent innovations in handheld mobile device technology, the capabilities ofmobile augmented reality have taken a leap as well. Many companies are investing in thistechnology to optimize their internal and external processes. This research aims to provideinsights into the relation between mobile …