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Clinimetrics

Emmylou Beekman (Lector); Sandra Lüttmann

Description: The Neck Pain and Disability Scale (NPDS or NPAD) is a questionnaire aiming to quantify neck pain and disability.1 It is a patient-reported outcome measure for patients with any type of neck pain, of any duration, with or without injury.1,2 It consists of 20 items: three related to pain …

2021-10-01GezondheidArtikel

Differences in mortality in critically ill elderly patients during the second COVID-19 surge in Europe

COVIP Study Group

BACKGROUND: The primary aim of this study was to assess the outcome of elderly intensive care unit (ICU) patients treated during the spring and autumn COVID-19 surges in Europe. METHODS: This was a prospective European observational study (the COVIP study) in ICU patients aged 70 years and older admitted …

2021-09-23AlgemeenArtikel

Presence or Absence of Skeletal Muscle Dysfunction in Chronic Obstructive Pulmonary Disease is Associated With Distinct Phenotypes

C.L. Cruthirds; Barbara van der Meij; A. Wierzchowska-McNew; N.E.P. Deutz; M.P.K.J. Engelen

2021AlgemeenArtikel

Measurement of range-of-motion in infants with indications of upper cervical dysfunction using the Flexion-Rotation-Test and Lateral-Flexion-Test: a blinded inter-rater reliability study in a clinical practice setting.

F. Driehuis; N.L.W. Keijsers; Ria Nijhuis-van der Sanden; R.A. de Bie; Bart Staal; T.J. Hoogeboom

Background: In infants with indications of upper cervical dysfunction, the Flexion-Rotation-Test and Lateral-Flexion-Test are used to indicate reduced upper cervical range-of-motion (ROM). In infants, the inter-rater reliability of these tests is unknown. Objective: To assess the inter-rater reliability …

2021AlgemeenArtikel

Intramuscular short-chain acylcarnitines in elderly people are decreased in (pre-)frail females, but not in males.

Marjanne van der Hoek (Onderzoeker); Arie Nieuwenhuizen (Onderzoeker); Ondřej Kuda (Onderzoeker); Paul Bos (Onderzoeker); Veronika Paluchová (Onderzoeker); Lars Verschuren (Onderzoeker); Anita van den Hoek (Onderzoeker); Robert Kleemann (Onderzoeker); Nic Veeger (Onderzoeker); Feike van der Leij (Lector); Jaap Keijer (Onderzoeker)

We tested the hypothesis that in human ageing a decreased intramuscular acylcarnitine status is associated with (pre-)frailty, reduced physical performance and altered mitochondrial function. Results showed that intramuscular total carnitine levels and acetylcarnitine levels were lower in (pre-)frail …

2020-06-15GezondheidArtikel

Sepsis at ICU admission does not decrease 30-day survival in very old patients

VIP1 study; Dieperink, Willem

BACKGROUND: The number of intensive care patients aged ≥ 80 years (Very old Intensive Care Patients; VIPs) is growing. VIPs have high mortality and morbidity and the benefits of ICU admission are frequently questioned. Sepsis incidence has risen in recent years and identification of outcomes is of considerable …

2020-05-13AlgemeenArtikel

"Waar komt de stijging van conventionele defecografie in de Tjongerschans vandaan?"

Manon Groesz (Student); Anna Hartsema (Student); Patrick Schenkers (Begeleider); Annemieke van der Heij-Meijer (Begeleider)

Het doel van de studie is het in kaart brengen wat de oorzaak van de stijging van het aantal uitgevoerde defecografie onderzoeken binnen de Tjongerschans is, ondanks de alternatieven. MRI-D en DAE worden in de literatuur als alternatieven gezien. Van de respondenten vindt 69% MRI-D een goed alternatief …

2020-01-10GezondheidBachelor

Validity of Clinical Measurement Instruments Assessing Scapular Function

Norman D'Hondt (Onderzoeker); Jan Pool (Lid Lectoraat); Henri Kiers (Lid Lectoraat); Charlotte Terwee; Dirkjan Veeger

Objective: To determine the construct validity, criterion validity, and responsiveness of measurement instruments evaluating scapular function. Design: Systematic review of measurement properties. Literature Search: The MEDLINE, Embase, CINAHL, and SPORTDiscus databases were systematically searched …

2020GezondheidArtikel

Hoofdpijn en temporomandibulaire disfunctie

van der Meer, Hedwig; Visscher, Corine; Speksnijder, Caroline

2019-04AlgemeenArtikel

Screening of novel HSP-inducing compounds to conserve cardiomyocyte function in experimental atrial fibrillation

Heeres, André (Biobased Ingredients And Materials); Xu, Hu; van Marion, Denise MS; Hoogstra-Berends, Femke; Zhang, Deli; Seerden, Jean-Paul; Loen, Lizette; Steen, Herman; Henning, Robert H; Brundel, Bianca J J M

Background: The heat shock protein (HSP) inducer, geranylgeranylacetone (GGA), was previously found to protect against atrial fibrillation (AF) remodeling in experimental model systems. Clinical application of GGA in AF is limited, due to low systemic concentrations owing to the hydrophobic character …

2019-01-18AlgemeenArtikel

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