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Docosahexaenoyl Serotonin, an endogenously formed n-3 fatty acid-serotonin conjugate has anti-inflammatory properties by attenuating IL-23–IL-17 signalling in macrophages

Jean Paul ten Klooster (Lid Lectoraat); Raymond Pieters (Lector); Mieke Polanda; Zheng Wang; Renger Witkamp; Jocelijn Meijerink; Mark Boekschoten

Abstract from the article: "Conjugates of fatty acids and amines, including endocannabinoids, are known to play important roles as endogenous signaling molecules. Among these, the ethanolamine conjugate of the n-3 poly unsaturated long chain fatty acid (PUFA) docosahexaenoic acid (22:6n-3) (DHA) was …

2016-09-26Gezondheid; …Artikel

The structure of wheat bread influences the postprandial metabolic response in healthy men

Eelderink, Coby; Noort, Martijn W.J.; Sozer, Nesli; Koehorst, Martijn; Holst, Jens J.; Deacon, Carolyn F.; Rehfeld, Jens F.; Poutanen, Kaisa; Vonk, Roel J.; Oudhuis, Lizette (Healthy Food & Nutrition); Priebe, Marion G.

Postprandial high glucose and insulin responses after starchy food consumption, associated with an increased risk of developing several metabolic diseases, could possibly be improved by altering food structure. We investigated the influence of a compact food structure; different wheat products with a …

2015-08-07AlgemeenArtikel

The role of Coproporphyrinogen III oxidase and Ferrochelatase genes in heme biosynthesis and regulation in Aspergillus niger

C.A. van den Hondel; P.J. Punt; H. Haas; Arthur F.J. Ram; M. Werner; S. de Weert; A.C. Franken; Christien Lokman

Heme is a suggested limiting factor in peroxidase production by Aspergillus spp., which are well-known suitable hosts for heterologous protein production. In this study, the role of genes coding for coproporphyrinogen III oxidase (hemF) and ferrochelatase (hemH) was analyzed by means of deletion and …

2013AlgemeenArtikel

Endogenous sex hormones and subclinical atherosclerosis in middle-aged and older men

Marieke Schuurmans (Lector); Michiel Bots; Judith Brandt; Marjolein den Ouden; Yvonne van der Schouw

Circulating sex hormone levels have been linked to a wide range of cardiovascular risk factors in men, but studies on incident CVD have been inconclusive [1]. Recent data from meta-analyses show an increase in CVD risk with low testosterone in elderly men and no association with estradiol levels …

2013AlgemeenArtikel

Locked-in sticky textbooks: mainstream teaching of the money supply process

M.A. Boermans (Lid Lectoraat); B.J. Moore

Current macro-economic textbooks provide a fatally misleading description of the money supply process in modern economies. Over the past 20 years Post Keynesian authors have established conclusively that despite strictly-enforced cash reserve requirements, changes in the supply of bank deposits are not …

2008AlgemeenBoekdeel

Dutch Sport Federations Changing into Market Oriented Organizations: The Institutional Theory Applied on Three Case Studies

Marije van 't Verlaat (Docent)

In 2005 and 2006, almost sixty Dutch National Sport Federations (NSFs) participated in a special program for creating a marketing strategy for the next four years. This program was initiated and organized by NOC*NSF (the Dutch Olympic Umbrella Sports Organization). The NSFs had to joint the project to …

2007Economie & ManagementConferentiebijdrage

Reduced oxidation rates of ingested glucose during prolonged exercise with low endogenous CHO availability

A.E. Jeukendrup; L.B. Borghouts (Lector); W.H.M. Saris; A.J.M. Wagenmakers

This paper descibes a study that shows that glycogen-lowering exercise, performed the evening before an exercise bout in combination with glycogen restriction leads to a reduction of the oxidation rate of ingested glucose during moderate-intensity exercise

1996AlgemeenArtikel

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