BACKGROUND The mechanical power of ventilation (MP) has an association with outcome in invasively ventilated patients with the acute respiratory distress syndrome (ARDS). Whether a similar association exists in invasively ventilated patients without ARDS is less certain. OBJECTIVE To investigate the …

Background: In hospitalized patients with COVID-19, the dosing and timing of corticosteroids vary widely. Low-dose dexamethasone therapy reduces mortality in patients requiring respiratory support, but it remains unclear how to treat patients when this therapy fails. In critically ill patients, high-dose …

INTRODUCTION: Mechanical Insufflation-Exsufflation (MI-E) is used as an airway clearance intervention in primary care (home ventilation), long-term care (prolonged rehabilitation after intensive care, neuromuscular diseases, and spinal cord injury), and increasingly in acute care in intensive care units …

Introduction The driving pressure (ΔP) has an independent association with outcome in patients with acute respiratory distress syndrome (ARDS). INTELLiVENT-Adaptive Support Ventilation (ASV) is a closed-loop mode of ventilation that targets the lowest work and force of breathing. Aim To compare transpulmonary …

Background Fluid therapy is a common intervention in critically ill patients. It is increasingly recognised that deresuscitation is an essential part of fluid therapy and delayed deresuscitation is associated with longer invasive ventilation and length of intensive care unit (ICU) stay. However, optimal …

Mechanical insufflation-exsufflation (MI-E) is traditionally used in the neuromuscular population. There is growing interest of MI-E use in invasively ventilated critically ill adults. We aimed to map current evidence on MI-E use in invasively ventilated critically ill adults. Two authors independently …

We weten steeds meer van onze bekende Nederlanders. Dit gaat van weten waar ze op vakantie zijn tot weten of ze ooit iemand hebben misbruikt. Waar het bij veel soorten media blijft bij het melden van de informatie, ondernemen radiostations actie. Blijf je een artiest draaien of haal je zijn muziek van …

This thesis is written on behalf of AFRIEK. AFRIEK is a fashion brand based in Rwanda which has the vision to show the power of cross-cultural collaboration based on equality. AFRIEK became much more of a research project than only a commercial brand: trying to be as sustainable as possible while keeping …

Dit rapport is geschreven naar aanleiding van het onderzoek naar de onveiligheidsgevoelens van de medewerkers van de Beschermd Wonen locaties in gebied B binnen Stichting Anton Constandse. De opdrachtgever gaf aan behoefte te hebben aan een onderzoek naar het onveiligheidsgevoel van de medewerkers tegenover …

BACKGROUND: The SpO2/FiO2 is a useful oxygenation parameter with prognostic capacity in patients with ARDS. We investigated the prognostic capacity of SpO2/FiO2 for mortality in patients with ARDS due to COVID-19. METHODS: This was a post-hoc analysis of a national multicenter cohort study in invasively …