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The impact of high versus standard enteral protein provision on functional recovery following intensive care admission (PRECISE trial): study protocol for a randomized controlled, quadruple blinded, multicenter, parallel group trial in mechanically ventilated patients

Rob J.J. van Gassel (Onderzoeker); Julia L.M. Bels (Onderzoeker); Katrien Tartaglia (Onderzoeker); Bas C.T. Bussel (Onderzoeker); Sander M.J. van Kuijk (Onderzoeker); Adam M. Deane (Onderzoeker); Zudin Puthucheary (Onderzoeker); Peter Weijs (Onderzoeker); Lilian Vloet (Lector); Bert (A.) Beishuizen (Onderzoeker); Ashley de Bie Dekker (Onderzoeker); Vincent Fraipont (Onderzoeker); Stoffel Lamote (Onderzoeker); Didier Ledoux (Onderzoeker); Clarissa Scheeren (Onderzoeker); Elisabeth de Waele (Onderzoeker); Arthur R.H. van Zanten (Onderzoeker); Dieter Mesotten (Onderzoeker); Marcel C.G. van de Poll (Onderzoeker)

Critically ill patients are subject to severe skeletal muscle wasting during intensive care unit (ICU) stay, resulting in impaired short- and long-term functional outcomes and health-related quality of life. Increased protein provision may improve functional outcomes in ICU patients by attenuating skeletal …

2023-06-19GezondheidArtikel

Supportive care for relatives of patients dying in the intensive care setting: development of a toolbox (Project STRIC)

F.E. Witkamp; D. Enfield; R. Marijnissen-de Jong; D. Bolman; M. Bulut; J. Geraerdts; M. van de Haas; G. Konink; P. Spronk; C. den Uil; L. Vloet; S. Wagener; M. van Mol

The Intensive Care Unit (ICU) is characterised by high tech and absence of intimacy and often lacks a structured palliative care approach for bereavement support for relatives. We developed practical tools for ICU-nurses in the Netherlands to support relatives of dying patients in the ICU.

2023-05-16GezondheidAndersoortig materiaal

Relatives' experiences of the transition from intensive care to home for acutely admitted intensive care patients

Meiring-Noordstra, Aaltje; van der Meulen, Ingeborg C; Onrust, Marisa; Hafsteinsdóttir, Thóra B; Luttik, Marie Louise (Family Care)

BACKGROUND: Acute admission to an intensive care unit (ICU) can negatively affect quality of life for patients and their relatives. Relatives play an important caregiving role after the patient's admission. More knowledge and understanding of their needs are necessary as the patient transitions home. …

2023-05-08AlgemeenArtikel

Incidence of Air Leaks in Critically Ill Patients with Acute Hypoxemic Respiratory Failure Due to COVID-19

Goossen, Robin L.; Verboom, Mariëlle; Blacha, Mariëlle; Smesseim, Illaa; Beenen, Ludo F. M.; van Meenen, David M. P.; Paulus, Frederique (Lectoraat Critical Care); Schultz, Marcus J.

Subcutaneous emphysema, pneumothorax and pneumomediastinum are well-known complications of invasive ventilation in patients with acute hypoxemic respiratory failure. We determined the incidences of air leaks that were visible on available chest images in a cohort of critically ill patients with acute …

2023-03AlgemeenArtikel

Effect of mechanical power on mortality in invasively ventilated ICU patients without the acute respiratory distress syndrome

van Meenen, David M.P.; Algera, Anna Geke; Schuijt, Michiel T.U.; Simonis, Fabienne D.; van der Hoeven, Sophia M.; Neto, Ary Serpa; Abreu, Marcelo Gama de; Pelosi, Paolo; Paulus, Frederique (Lectoraat Critical Care); Schultz, Marcus J.

BACKGROUND The mechanical power of ventilation (MP) has an association with outcome in invasively ventilated patients with the acute respiratory distress syndrome (ARDS). Whether a similar association exists in invasively ventilated patients without ARDS is less certain. OBJECTIVE To investigate the …

2023-01AlgemeenArtikel

Patients with and without COVID-19 in the Intensive Care Unit: Physical Status Outcome Comparisons 3 Months after Discharge

Bas Cijs (Onderzoeker); Karin Valkenet (Onderzoeker); Germijn Heijnen (Onderzoeker); Anne Visser‑Meily (Onderzoeker); Marike van der Schaaf (Onderzoeker)

Objective: Many patients with COVID-19 infections were admitted to an intensive care unit (ICU). Physical impairments are common after ICU stays and are associated with clinical and patient characteristics. To date, it is unknown if physical functioning and health status are comparable between patients …

2023GezondheidArtikel

Mechanical insufflation-exsufflation for invasively ventilated critically ill patients

Stilma, Willemke (Faculteit Gezondheid); Verweij, Lotte; Spek, Bea; Scholte Op Reimer, Wilhelmina Johanna Maria; Schultz, Marcus Josephus; Paulus, Frederique (Lectoraat Critical Care); Rose, Louise

INTRODUCTION: Mechanical Insufflation-Exsufflation (MI-E) is used as an airway clearance intervention in primary care (home ventilation), long-term care (prolonged rehabilitation after intensive care, neuromuscular diseases, and spinal cord injury), and increasingly in acute care in intensive care units …

2023AlgemeenArtikel

Course of recovery of respiratory muscle strength and its associations with exercise capacity and handgrip strength: A prospective cohort study among survivors of critical illness

Major, Mel (Centre Of Expertise Urban Vitality); van Egmond, Maarten (Lectoraat Fysiotherapie - Transitie Van Zorg Bij Complexe Patiënten); Dettling-Ihnenfeldt, Daniela; Ramaekers, Stephan (Lectoraat Fysiotherapie - Transitie Van Zorg Bij Complexe Patiënten); Engelbert, Raoul (Lectoraat Fysiotherapie - Transitie Van Zorg Bij Complexe Patiënten); van der Schaaf, Marike (Lectoraat Revalidatie In De Acute Zorg)

Background Mechanical ventilation affects the respiratory muscles, but little is known about long-term recovery of respiratory muscle weakness (RMW) and potential associations with physical functioning in survivors of critical illness. The aim of this study was to investigate the course of recovery of …

2023AlgemeenArtikel

Open or closed suctioning in invasively ventilated patients for sustainibility of ICU care?

Stilma, W. (Centre Of Expertise Urban Vitality); Esmeijer, A.; Paulus, F. (Lectoraat Critical Care); Frenzel, T.; Touw, H.; Stobernack, T.

2023AlgemeenConferentiebijdrage

Broadening the Berlin definition of ARDS to patients receiving high-flow nasal oxygen

van der Ven, Fleur Stefanie L.I.M.; Valk, Christel M.A.; Blok, Siebe; Brouwer, Michelle G.; Go, Dai Ming; Lokhorst, Amanda; Swart, Pien; van Meenen, D. M.; Paulus, F. (Lectoraat Critical Care); Schultz, Marcus J.

Background High-flow nasal oxygen (HFNO) is increasingly used in patients with acute hypoxemic respiratory failure. It is uncertain whether a broadened Berlin definition of acute respiratory distress syndrome (ARDS), in which ARDS can be diagnosed in patients who are not receiving ventilation, results …

2023AlgemeenArtikel

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