Background To improve transmural palliative care for older adults acutely admitted to hospital, the PalliSupport intervention, comprising an educational programme and transmural palliative care pathway, was developed. This care pathway involves timely identification of palliative care needs, advance …

Background: Postoperative complications and readmissions to hospital are factors known to negatively influence the short- and long-term quality of life of patients with gastrointestinal cancer. Active family involvement in activities, such as fundamental care activities, has the potential to improve …

Sinds 7 jaar wordt een nieuw beleid gehanteerd omtrent een SRM (Small Renal Mass). Van de tumor wordt nu eerst een RTB (Renale Tumor Biopsie) genomen om te beoordelen of de tumor maligne of benige is. Met dit praktijkgericht onderzoek wordt een aanbeveling gedaan of het nieuwe beleid toereikend is. De …

Background: A nodular lymphocyte predominant Hodgkin's lymphoma (NLPHL) is a lymphoproliferative neoplasm with a fair prognosis, but the possibility of a malignant transformation into a diffuse large B-cell lymphoma (DLBCL) is high. DLBCL progresses aggressively. Introduction of rituximab into therapy …

Cutaneous melanoma is a type of skin cancer that develops from benign melanocytes to one of the most aggressive types of skin tumors in human. In cutaneous melanoma progression, the metastasis phase is the most challenging phase to treat. To enable earlier treatment options, a better understanding of …

The thesis project was devoted to a differentiation of different types of cancer cells checking the effectiveness of the novel anti-leukemia chemicals and exploring whether the best anti-leukemia targets also target bone cancers. The research question of this project is as follows: “How leukemia and …

Introduction: Uveal melanoma (UM) is a common tumor in the eye. The uvea is with 82% the most frequent site of origin of ocular melanomas in the western world and has an incidence of 4 to 5 per million in the Netherlands. Uveal melanoma arises from melanocytes located in the uveal tract of the eye. …

Purpose With current diagnostic methods, the majority of patients with symptomatic colorectal anastomotic leakage (CAL) is identified approximately 1 week after operation. The aim of this study is to determine whether real-time polymerase chain reaction (RT-PCR) for detection of Escherichia coli and …