Abstract: Plan adaptation during the course of (chemo)radiotherapy of H&N cancer requires repeat CT scanning to capture anatomy changes such as parotid gland shrinkage. Hydration, applied to prevent nephrotoxicity from cisplatin, could temporarily alter the hydrogen balance and hence the captured anatomy. …

Purpose: to find parameters that predict which head and neck patients benefit from a sequentially delivered boost treatment plan compared to a simultaneously deliverd plan, with the aim to spare the salivary glands.