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The impact of high versus standard enteral protein provision on functional recovery following intensive care admission (PRECISE trial)

van Gassel, Rob J. J.; Bels, Julia L. M.; Tartaglia, Katrien; van Bussel, Bas C. T.; van Kuijk, Sander M. J.; Deane, Adam M.; Puthucheary, Zudin; Weijs, Peter J. M. (Lectoraat Voeding En Beweging); Vloet, Lilian; Beishuizen, Bert; De Bie Dekker, Ashley; Fraipont, Vincent; Lamote, Stoffel; Ledoux, Didier; Scheeren, Clarissa; De Waele, Elisabeth; van Zanten, Arthur R. H.; Mesotten, Dieter; van de Poll, Marcel C. G.

Background Critically ill patients are subject to severe skeletal muscle wasting during intensive care unit (ICU) stay, resulting in impaired short- and long-term functional outcomes and health-related quality of life. Increased protein provision may improve functional outcomes in ICU patients by attenuating …

2023AlgemeenArtikel

Effect of lung ultrasound-guided fluid deresuscitation on duration of ventilation in intensive care unit patients (CONFIDENCE)

Blok, Siebe G.; Mousa, Amne; Brouwer, Michelle G.; de Grooth, Harm-Jan; Neto, Ary Serpa; Blans, Michiel J.; den Boer, Sylvia; Dormans, Tom; Endeman, Henrik; Roeleveld, Timo; Scholten, Harm; van Slobbe-Bijlsma, Eline R.; Scholten, Erik; Touw, Hugo; van der Ven, Fleur Stefanie L. I. M.; Wils, Evert-Jan; van Westerloo, David J.; Heunks, Leo M. A.; Schultz, Marcus J.; Paulus, Frederique (Lectoraat Critical Care); Tuinman, Pieter R.

Background Fluid therapy is a common intervention in critically ill patients. It is increasingly recognised that deresuscitation is an essential part of fluid therapy and delayed deresuscitation is associated with longer invasive ventilation and length of intensive care unit (ICU) stay. However, optimal …

2023AlgemeenArtikel

Open or closed suctioning in invasively ventilated patients for sustainibility of ICU care?

Stilma, W. (Centre Of Expertise Urban Vitality); Esmeijer, A.; Paulus, F. (Lectoraat Critical Care); Frenzel, T.; Touw, H.; Stobernack, T.

2023AlgemeenConferentiebijdrage

Early high protein provision and mortality in ICU patients including those receiving continuous renal replacement therapy

van Ruijven, Isabel M. (Lectoraat Voeding En Beweging); Stapel, Sandra N.; Girbes, Armand R. J.; Weijs, Peter J. M. (Lectoraat Voeding En Beweging)

BACKGROUND: Findings on the association between early high protein provision and mortality in ICU patients are inconsistent. The relation between early high protein provision and mortality in patients receiving CRRT remains unclear. The aim was to study the association between early high protein provision …

2022-09AlgemeenArtikel

The Use of Mechanical Insufflation-Exsufflation in Invasively Ventilated Critically Ill Adults

Swingwood, Ema L; Stilma, Willemke (Faculteit Gezondheid); Tume, Lyvonne N; Cramp, Fiona; Voss, Sarah; Bewley, Jeremy; Ntoumenopoulos, George; Schultz, Marcus J; Scholte Op Reimer, Wilma; Paulus, Frederique (Lectoraat Critical Care); Rose, Louise

Mechanical insufflation-exsufflation (MI-E) is traditionally used in the neuromuscular population. There is growing interest of MI-E use in invasively ventilated critically ill adults. We aimed to map current evidence on MI-E use in invasively ventilated critically ill adults. Two authors independently …

2022-08-01AlgemeenAndersoortig materiaal

Association between early cumulative fluid balance and successful liberation from invasive ventilation in COVID-19 ARDS patients - insights from the PRoVENT-COVID study

BACKGROUND: Increasing evidence indicates the potential benefits of restricted fluid management in critically ill patients. Evidence lacks on the optimal fluid management strategy for invasively ventilated COVID-19 patients. We hypothesized that the cumulative fluid balance would affect the successful …

2022-06-01AlgemeenArtikel

Steps to recovery: Body weight-supported treadmill training for critically ill patients: A randomized controlled trial

Kwakman, Robin C.H. (Faculteit Gezondheid); Voorn, Eric L.; Horn, Janneke; Nollet, Frans; Engelbert, Raoul H.H. (Lectoraat Fysiotherapie - Transitie Van Zorg Bij Complexe Patiënten); Sommers, Juultje; van der Schaaf, Marike (Lectoraat Revalidatie In De Acute Zorg)

Purpose Early mobilization of critically ill patients improves functional recovery, but is often hampered by tubes, drains, monitoring devices and muscular weakness. A mobile treadmill with bodyweight support facilitates early mobilization and may shorten recovery time to independent ambulation as compared …

2022-06AlgemeenArtikel

Prognostication using SpO2/FiO2 in invasively ventilated ICU patients with ARDS due to COVID-19 - Insights from the PRoVENT-COVID study

Roozeman, Jan-Paul; Mazzinari, Guido; Serpa Neto, Ary; Hollmann, Markus W.; Paulus, Frederique (Lectoraat Critical Care); Schultz, Marcus J.; Pisani, Luigi

BACKGROUND: The SpO2/FiO2 is a useful oxygenation parameter with prognostic capacity in patients with ARDS. We investigated the prognostic capacity of SpO2/FiO2 for mortality in patients with ARDS due to COVID-19. METHODS: This was a post-hoc analysis of a national multicenter cohort study in invasively …

2022-04AlgemeenArtikel

Association of early positive end-expiratory pressure settings with ventilator-free days in patients with coronavirus disease 2019 acute respiratory distress syndrome

BACKGROUND : There is uncertainty about how much positive end-expiratory pressure (PEEP) should be used in patients with acute respiratory distress syndrome (ARDS) due to coronavirus disease 2019 (COVID-19). OBJECTIVE : To investigate whether a higher PEEP strategy is superior to a lower PEEP strategy …

2021-12AlgemeenArtikel

Incidence and Practice of Early Prone Positioning in Invasively Ventilated COVID-19 Patients-Insights from the PRoVENT-COVID Observational Study

Stilma, Willemke (Faculteit Gezondheid); van Meenen, David M. P.; Valk, Christel M. A.; de Bruin, Hendrik; Paulus, Frederique (Centre Of Expertise Urban Vitality); Serpa Neto, Ary; Schultz, Marcus J.

We describe the incidence and practice of prone positioning and determined the association of use of prone positioning with outcomes in invasively ventilated patients with acute respiratory distress syndrome (ARDS) due to coronavirus disease 2019 (COVID-19) in a national, multicenter observational study, …

2021-10AlgemeenArtikel

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