In de agro-chemie industrie wordt tegenwoordig een grote hoeveelheid data gegenereerd. De inzet van sensoren voor het monitoren van productieprocessen, het sequensen van gewassen en het karakteriseren van bodemmonsters zijn voorbeelden van activiteiten die veel data opleveren. Tegelijkertijd dalen de …

Op donderdag 12 november 2020 organiseert het Kennisnetwerk Data Science een webinar over Data Science for Life Sciences. Wynand Alkema, Lector Data Science aan de Hanzehogeschool Groningen, zal een introductie verzorgen over hoe data science wordt toegepast in Life Sciences en welke technieken worden …

Large scale integration of PubMed with x-omics data sets for the discovery of biological networks

Systemic sclerosis (SSc) is an autoimmune disease which is characterized by vasculopathy, tissue fibrosis and activation of the innate and adaptive immune system. Clinical features of the disease consists of skin thickening and internal organ involvement. Due to the heterogeneous nature of the disease …

Klotho knock-out mice are an important model for vascular calcification, which is associated with chronic kidney disease. In chronic kidney disease, serum magnesium inversely correlates with vascular calcification. Here we determine the effects of serum magnesium on aortic calcification in Klotho knock-out …

In the production of fermented foods, microbes play an important role. Optimization of fermentation processes or starter culture production traditionally was a trial-and-error approach inspired by expert knowledge of the fermentation process. Current developments in high-throughput 'omics' technologies …

In this study we tested 39 Lactococcus lactis strains isolated from diverse habitats for their robustness under heat and oxidative stress, demonstrating high diversity in survival (up to 4 log units). Strains with an L. lactis subsp. lactis phenotype generally displayed more-robust phenotypes than strains …

Synthetic glucocorticoids are potent anti-inflammatory drugs but show dose-dependent metabolic side effects such as the development of insulin resistance and obesity. The precise mechanisms involved in these glucocorticoid-induced side effects, and especially the participation of adipose tissue in this …