This report describes the work that has been done on the water calorimeter project at VSL. The calorimeter determines the absorbed-dose-to water Dw in gray, by measuring the radiation induced temperature change. The temperature of the water will change due to irradiation of a beam ionizing radiation. …

Research has been done to improve the understanding the self-heat effect, due to power dissipation, of temperature-dependant resistors in the VSL water calorimeter. A custom measurement program has been written to be able to control and read out three Agilent 3458A digital multimeters (DMMs). With these …

Synthetic glucocorticoids are potent anti-inflammatory drugs but show dose-dependent metabolic side effects such as the development of insulin resistance and obesity. The precise mechanisms involved in these glucocorticoid-induced side effects, and especially the participation of adipose tissue in this …

Background: Glucocorticoids are potent anti-inflammatory agents used for the treatment of diseases such as rheumatoid arthritis, asthma, inflammatory bowel disease and psoriasis. Unfortunately, usage is limited because of metabolic side-effects, e.g. insulin resistance, glucose intolerance and diabetes. …

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Achtergrond: Fysiotherapie is een belangrijk onderdeel van de multidisciplinaire behandeling van patiënten met COPD. De fysiotherapeutische behandeling kan zich richten op de kortademigheid, het verminderde activiteitenniveau, de verminderde perifere spierkracht en de verminderde inspanningscapaciteit. …

BACKGROUND: The treatment-related burden for patients undergoing hematopoietic stem cell transplantation (HSCT) may be relieved by physical exercises. PURPOSE: The purpose of this study was to summarize and analyze the evidence provided by randomized controlled trials (RCTs) on physical exercise interventions …

Rian de Waal (1958-2011) has written a book about the piano, and how the development of piano playing has been very much dependent upon musicians who were able to cross borders. In Metamorphoses, the Art of the Virtuoso Piano Transcription, De Waal takes us on a journey through the capricious history …

Background Fatness and fitness both influence cardiometabolic risk. Objective The purpose of this study was to investigate whether childhood fatness and increasing fatness from childhood to adolescence are associated with cardiometabolic risk during adolescence and how fitness affects this association. …

According to the "membrane sensor" hypothesis, the membrane's physical properties and microdomain organization play an initiating role in the heat shock response. Clinical conditions such as cancer, diabetes and neurodegenerative diseases are all coupled with specific changes in the physical state and …