An activity-friendly environment may increase physical activity (PA) levels and decrease sedentary behavior (SB). This study investigated associations between socio-demographic characteristics, health-related quality of life (HRQoL), perceived environment and objectively measured PA outcomes. Socio-demographic …

The objective of the study described in this paper is to define safety metrics that are based on the utilisation of resources. The background of this research is a specific need of the aviation industry where small and medium-sized enterprises lack large amounts of safety-related data to measure and …

For hypertensive women in CHIPS (Control of Hypertension in Pregnancy Study), we assessed whether the maternal benefits of tight control could be achieved, while minimizing any potentially negative effect on fetal growth, by delaying initiation of antihypertensive therapy until later in pregnancy. For …

Objective To evaluate the effectiveness of a comprehensive workers’ health surveillance (WHS) program on aspects of sustainable employability and cost-benefit. Methods A cluster randomized stepped wedge trial was performed in a Dutch meat processing company from february 2012 until march 2015. In total …

Het hbo kampt met gering studiesucces van studenten in termen van studievoortgang, uitval en gepercipieerde competentie. Welke maatregelen kan het hbo nemen? Deze bijdrage, gebaseerd op het proefschrift ‘One size fits all?’, gaat over leerpsychologische factoren en interactionalistische factoren waaruit …

Metformin prevents weight gain in patients with type 2 diabetes (T2D). However, the mechanisms involved are still unknown. In this post hoc analysis of the HOME trial, we aimed to determine whether metformin affects energy intake. Patients with T2D were treated with 850 mg metformin or received placebo …

Background: Aging is accompanied by a progressive loss of muscle mass and muscle strength, also called sarcopenia. Adequate protein intake and distribution influences myofibrillar protein synthesis (MPS) and might therefore be important in the prevention of sarcopenia. Whether the daily amount and distribution …

The Dutch population is aging. Aging is associated with low muscle mass, strength and function, also known as sarcopenia. Sarcopenia leads to several problems as falling more often, physical frailty, disability and a higher risk of mortality. Additionally, absorption of many nutrients decreases with …

Goal: The goal of this thesis is to study the association between protein intake and the change in lean mass during a cutting and a bulking phase. The term cutting means being in a caloric deficit for a period of time to reduce the amount of body fat and maintain as much muscle mass as possible. The …

Background: Neck pain is the fourth major cause of disability worldwide but sufficient evidence regarding treatment is not available. This study is a first exploratory attempt to gain insight into and consensus on the clinical reasoning of experts in patients with non-specific neck pain. Objective: …