Objective: To explore the nature and extent of possible residual complaints among Dutch hypothyroid patients using thyroid replacement therapy, we initiated a comprehensive study measuring health-related quality of life (QoL), daily functioning, and hypothyroidism-associated symptoms in patients and …

Background People with intellectual disabilities (ID) have a lower life expectancy than their peers without ID. A contributing factor to the lower life expectancy and early mortality could be sarcopenia: low muscle mass and low muscle function. In the general population, sarcopenia strongly predicts …

Objective To investigate trends in low Apgar scores in (near) term singletons using the Dutch Perinatal Registry. Methods In a cohort of 1,583,188 singletons liveborn ≥35 weeks of gestation in the period 2010–2019, we studied trends in low 5-min Apgar scores (<7 and <4) using Cochrane Armitage trend …

Background In the Netherlands, general practitioners (GPs) play a key role in HIV testing. However, the proportion of people diagnosed with late-stage HIV remains high, and opportunities for earlier diagnosis are being missed. We implemented an educational intervention to improve HIV and STI testing …

OBJECTIVES: The aim of this study was to evaluate the association between integrated care and health-related quality of life (HRQOL) in a primary care practice population. DESIGN: A cross-sectional survey study. SETTING: Primary care practice population. PARTICIPANTS: A sample (n=5562) of patients in …

BACKGROUND: Since the placenta also has a sex, fetal sex-specific differences in the occurrence of placenta-mediated complications could exist. OBJECTIVE: To determine the association of fetal sex with multiple maternal pregnancy complications. SEARCH STRATEGY: Six electronic databases Ovid MEDLINE, …

Maintaining independence is the most important goal of the majority of older people. The onset of disability in activities of daily living is one of the greatest threats to the ability of older people to live independently. Older people with a low socioeconomic status (SES) are at high risk of functional …

Background: The purpose of this study is to increase our understanding of environmental correlates that are associated with route choice during active transportation to school (ATS) by comparing characteristics of actual walking and cycling routes between home and school with the shortest possible route …

Background To describe the prevalence of multimorbidity and to study the association between acute and chronic diseases in acutely hospitalized older patients Methods Prospective cohort study conducted between 2006 and 2008 in three teaching hospitals in the Netherlands. 639 patients aged 65 years and …

Runners often sustain lower extremity injuries (19-79%) (van Gent et al, 2007). In a theoretical model it has been described that a disturbance in perceived stress and recovery can increase the risk of sustaining an injury (Williams & Andersen, 1998). Therefore, the purpose of this study was to investigate …