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Auto-Plan voor Oesophaguscarcinoom met VMAT

Laura Tax (Student); Inge Braspenning (Begeleider)

In het Radboudumc wordt een conventionele manuele plantechniek gehanteerd bij slokdarmkanker (1). Deze bestralingstechniek wordt handmatig geoptimaliseerd. Tegenwoordig kunnen Intensity Modulated Radiotion Therapy (IMRT) en Volumetric Arc Therapy (VMAT) bestralingsplannen doormiddel van de Auto-Plan …

2019GezondheidBachelor

Verschil in radiotherapeutische dosis bij het mammacarcinoom. Het effect van verschillende doelgebieden en planningstechnieken op de dosis in het doelgebied en risico-organen.

Myrthe Maas (Student); Silvia Enders (Begeleider)

In dit onderzoek zijn verschillende (sub)groepen van mammapatiënten geanalyseerd met de daarbij horende mean heart dose (MHD), mean lung dose (MLD) en mean clinical target volume dose (meanCTVdose). Hierbij is gekeken naar het verschil tussen 2013 en 2016 bij verschillende doelgebieden en planningstechnieken …

2017GezondheidBachelor

Prophylactic exercises among head and neck cancer patients during and after swallowing sparing intensity modulated radiation: Adherence and exercise performance levels of a 12-week guided home-based program

Ingrid Cnossen (Lid Lectoraat); Cornelia F. van Uden-Kraan; Birgit I. Witte; Yke J. Aalders; Cees J.T. de Goede; Remco de Bree; Patricia Doornaert; Derek H.F. Rietveld; Jan Buter; Johannes A. Langendijk; C. René Leemans; Irma M. Verdonck-de Leeuw

The background and purpose of this paper is to investigate adherence, exercise performance levels and associated factors in head and neck cancer (HNC) patients participating in a guided home-based prophylactic exercise program during and after treatment [swallowing sparing intensity modulated radiation …

2017GezondheidArtikel

Reconstruction of high resolution MLC leaf positions using a low resolution detector for accurate 3D dose reconstruction in IMRT

Visser, R.; Godart, J.; Wauben, D.J.L.; Langendijk, J.A.; van 't Veld, A.A.; Korevaar, E.W.

In pre-treatment dose verification, low resolution detector systems are unable to identify shifts of individual leafs of high resolution multi leaf collimator (MLC) systems from detected changes in the dose deposition. The goal of this study was to introduce an alternative approach (the shutter technique) …

2016-11-07AlgemeenArtikel

Prediction model to predict critical weight loss in patients with head and neck cancer during (chemo)radiotherapy

Langius, Jacqueline A.E.; Twisk, Jos; Kampman, Martine; Doornaert, Patricia; Kramer, Mark H.H.; Weijs, Peter J.M. (Lectoraat Voeding En Beweging); Leemans, C. René

OBJECTIVES: Patients with head and neck cancer (HNC) frequently encounter weight loss with multiple negative outcomes as a consequence. Adequate treatment is best achieved by early identification of patients at risk for critical weight loss. The objective of this study was to detect predictive factors …

2016-01AlgemeenArtikel

Development of an iterative reconstruction method to overcome 2D detector low resolution limitations in MLC leaf position error detection for 3D dose verification in IMRT

Visser, Ruurd; J., Godart; Wauben, D.J.L.; Langendijk, J.; van 't Veld, A.A.; Korevaar, E.W.

The objective of this study was to introduce a new iterative method to reconstruct multi leaf collimator (MLC) positions based on low resolution ionization detector array measurements and to evaluate its error detection performance. The iterative reconstruction method consists of a fluence model, a detector …

2016AlgemeenArtikel

Dose to the masseter muscle and risk of trismus after chemoradiation for advanced head & neck cancer

S Verheijen (Onderzoeker); Emmy Lamers (Lid Lectoraat)

Purpose / objective: Head and neck cancer patients treated with chemoradiation are at risk for developing trismus (reduced mouth opening). Trismus is often a persisting side-effect and difficult to manage. It impairs eating, speech and oral hygiene, affecting quality of life. Although several studies …

2015-12-01GezondheidAndersoortig materiaal

Multicriteria optimization enables less experienced planners to efficiently produce high quality treatment plans in head and neck cancer radiotherapy

Kierkels, Roel G J; Visser, Ruurd; Bijl, Hendrik P; Langendijk, Johannes A; van 't Veld, Aart A; Steenbakkers, Roel J H M; Korevaar, Erik W

OBJECTIVES: To demonstrate that novice dosimetry planners efficiently create clinically acceptable IMRT plans for head and neck cancer (HNC) patients using a commercially available multicriteria optimization (MCO) system. METHODS: Twenty HNC patients were enrolled in this in-silico comparative planning …

2015-04-12AlgemeenArtikel

Evaluation of DVH-based treatment plan verification in addition to gamma passing rates for head and neck IMRT

Visser, Ruurd; Wauben, David J.L.; de Groot, Martijn; Steenbakkers, Roel J.H.M.; Godart, Jeremy; van 't Veld, Aart A.; Langendijk, Johannes A.; Korevaar, Erik W.; Bijl, Hendrik P

Background and purpose: Treatment plan verification of intensity modulated radiotherapy (IMRT) is generally performed with the gamma index (GI) evaluation method, which is difficult to extrapolate to clinical implications. Incorporating Dose Volume Histogram (DVH) information can compensate for this. …

2014-09-01AlgemeenArtikel

Focal therapy bij patiënten met een prostaatcarcinoom

Maggie Klessens (Begeleider); `Jack Venselaar (Begeleider); Loes Spee (Student)

Het is moeilijk om eenduidig vast te stellen welke behandelingsmethode, Intensity Modulated Radiotherapy (IMRT) of High Dose Rate (HDR) brachytherapie, de voorkeur heeft bij focal therapy van patiënten met een prostaatcarcinoom. Het is nog onduidelijk wat de invloed van het prostaatvolume en de locatie …

2014GezondheidBachelor

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