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No evidence for stratified exercise therapy being cost-effective compared to usual exercise therapy in patients with knee osteoarthritis: Economic evaluation alongside cluster randomized controlled trial.

J. Knoop; J. Esser; J Dekker; J.W. de Joode; R.W.J.G. Ostelo; J.M. van Dongen

BACKGROUND: A stratified approach to exercise therapy may yield superior clinical and economic outcomes, given the large heterogeneity of individuals with knee osteoarthritis (OA). OBJECTIVE: To evaluate the cost-effectiveness during a 12-month follow-up of a model of stratified exercise therapy compared …

2022AlgemeenArtikel

Stratified exercise therapy does not improve outcomes compared with usual exercise therapy in people with knee osteoarthritis (OCTOPuS study): a cluster randomised trial.

J. Knoop; J Dekker; J.M. van Dongen; M van der Leeden; M. de Rooij; W.F. Peter; W. de Joode; L. van Bodegom-Vos; N. Lopuhaä; K.L. Bennell; W.F. Lems; M. van der Esch; T.P. Vliet Vlieland; R.W.J.G. Ostelo

QUESTION: In people with knee osteoarthritis, how much more effective is stratified exercise therapy that distinguishes three subgroups (high muscle strength subgroup, low muscle strength subgroup, obesity subgroup) in reducing knee pain and improving physical function than usual exercise therapy? DESIGN: …

2022AlgemeenArtikel

Patients' and clinicians' experiences with stratified exercise therapy in knee osteoarthritis: a qualitative study.

J. Knoop; J.W. de Joode; H. Brandt; J Dekker; R.W.J.G. Ostelo

BACKGROUND: We have developed a model of stratified exercise therapy that distinguishes three knee osteoarthritis (OA) subgroups ('high muscle strength subgroup', 'low muscle strength subgroup', 'obesity subgroup'), which are provided subgroup-specific exercise therapy (supplemented by a dietary intervention …

2022AlgemeenArtikel

Implementing a Personalized Physical Therapy Approach (Coach2Move) Is Effective in Increasing Physical Activity and Improving Functional Mobility in Older Adults: A Cluster-Randomized, Stepped Wedge Trial.

W. Heij; L. Sweerts; Bart Staal; S. Teerenstra; E. Adang; P.J. van der Wees; M.W.G. Nijhuis -van der Sanden; T.J. Hoogeboom

OBJECTIVE: The purpose of this study was to assess whether the superior cost-effectiveness of a personalized physical therapy approach (Coach2Move)-which was demonstrated in a previous trial when compared to usual care physical therapy (UCP)-can be replicated in daily clinical practice. METHODS: A multicenter …

2022AlgemeenArtikel

An Interprofessional Student-Run Medication Review Program

Rowan Sultan; Tessa O. van den Beukel; Michael O. Reumerman; Hester E.M. Daelmans; Hans Springer; Els Grijmans; Majon Muller; Milan C. Richir; Michiel A. van Agtmael; Jelle Tichelaar (Lector)

As the population ages, more people will have comorbid disorders and polypharmacy. Medication should be reviewed regularly in order to avoid adverse drug reactions and medication-related hospital visits, but this is often not done. As part of our student-run clinic project, we investigated whether an …

2021-10-04GezondheidArtikel

Toward assessing clinical trial publications for reporting transparency

Kilicoglu, Halil; Rosemblat, Graciela; Hoang, Linh; Wadhwa, Sahil; Peng, Zeshan; Malički, Mario; Schneider, Jodi; ter Riet, Gerben (Faculteit Gezondheid)

Objective: To annotate a corpus of randomized controlled trial (RCT) publications with the checklist items of CONSORT reporting guidelines and using the corpus to develop text mining methods for RCT appraisal. Methods: We annotated a corpus of 50 RCT articles at the sentence level using 37 fine-grained …

2021-04AlgemeenArtikel

Effects of a transitional care programme on medication adherence in an older cardiac population

Sara Daliri (Onderzoeker); Marcel J Kooij (Onderzoeker); Wilma JM Scholte op Reimer (Onderzoeker); Gerben ter Riet (Onderzoeker); Patricia Jepma (Onderzoeker); Lotte Verweij (Onderzoeker); Ron JG Peters (Onderzoeker); Bianca M Buurman (Onderzoeker); Fatma Karapinar-Çarkit (Onderzoeker)

Aims: Medication non-adherence post-discharge is common among patients, especially those suffering from chronic medical conditions, and contributes to hospital admissions and mortality. This study aimed to evaluate the effect of the Cardiac Care Bridge (CCB) intervention on medication adherence post-discharge. Methods: …

2021GezondheidArtikel

The Impact of Nursing Delirium Preventive Interventions in the ICU. A multicenter cluster-randomized controlled clinical trial

Paul Rood; M. Zegers; D. Ramnarain; M. Koopmans; T. Klarenbeek; E. Ewalds; M. van der Steen; A. Oldenbeuving; M. Kuiper; S. Teerenstra; E. Adang; L.M. van Loon; A. Wassenaar; H. Vermeulen; P. Pickkers; M. van den Boogaard

2021AlgemeenArtikel

The (cost-)effectiveness of an implemented fall prevention intervention on falls and fall-related injuries among community-dwelling older adults with an increased risk of falls: protocol for the in balance randomized controlled trial

van Gameren, Maaike; Bossen, Daniël (Lectoraat Oefentherapie); Bosmans, Judith E.; Visser, Bart (Centre Of Expertise Urban Vitality); Frazer, Sanne W. T.; Pijnappels, Mirjam

BACKGROUND: Falls and fall-related injuries among older adults are a serious threat to the quality of life and result in high healthcare and societal costs. Despite evidence that falls can be prevented by fall prevention programmes, practical barriers may challenge the implementation of these programmes. …

2021AlgemeenArtikel

Changes in inflammation and musculoskeletal tissue-derived biomarker serum levels in response to high- and low-intensity resistance training in individuals with knee osteoarthritis

Jansen, N.E.; Engstrøm, A.; Thudium, C.S.; Bay-Jensen, A-C.; de Zwart, A.H.; Dekker, J.; Lems, W.F.; Gerritsen, M.; van Spil, W.E.; Jaspers, R.T.; Turkstra, F.; van der Leeden, M.; van der Esch, M. (Lectoraat Interdisciplinaire Zorg Voor Chronische Gewrichtsaandoeningen)

Purpose: Exercise therapy with a focus on muscle strengthening has proven to be effective for the management of knee osteoarthritis (OA). Yet it is not known whether high-intensity resistance training (RT) is more effective in improving upper leg muscle strength and physical performance than low-intensity …

2020-04AlgemeenArtikel

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