Objectives: People with intellectual disabilities are more vulnerable to and experience mental health concerns at a higher incidence than their peers without intellectual disabilities. This may be directly related to the aetiology of their intellectual disability but also occur because of negative psychological …

Alzheimer's disease (AD) is the common neurodegenerative disorder and the most frequent cause of dementia. The disease accounts around 80% of all dementia diagnoses. The main reason of developing AD is amyloid cascade which starts from missense mutations in APP (amyloid precursor protein), Rho-associated …

It seems easier to talk about the end of humanity than about giving up the internet or giving up driving. It is argued that in our developed "first" world, we now need development aid ourselves. We are “blind” at the mercy of technological “progress”, which we continue to see against our better judgement, …

The age estimation of biological traces is one of the holy grails in forensic investigations. We developed a method for the age estimation of semen stains using fluorescence spectroscopy in conjunction with a stoichiometric ageing model. The model describes the degradation and generation rate of proteins …

This research justification aims at explaining the importance of the local customers for Bvlgari, Place Vendôme and how to recruit and retain them. The luxury industry is very competitive and the business needs to face a stiff competition. Innovation and development are keys and therefore, the shop needs …

Aim: We aim to gain insight into the interaction between challenging behavior as shown by individuals with an intellectual impairment, and space, and to explore the possibilities of using routinely collected data to this end. Background: Research on challenging behavior shown by intellectually impaired …

From past experience, the municipality of Groningen (GRO) knows that citizen engagement is an essential aspect to execute any plans that imply change. In particular, district energy plans need citizen engagement the most to ensure successful execution. Both GRO and Grunneger Power (GPO) have first-hand …

Background: Frailty in older adults is an increasing challenge for individuals, health care organizations and public health, both globally and in The Netherlands. To focus on frailty prevention from a public health perspective, understanding of frailty status is needed. To enable measurement of frailty …

The main objectives of this review were to: (1) review different methods/techniques to assess gaseous N-losses from manure (2) review N-gaps, attributed to dinitrogen loss as the difference between directly measured N compounds summed as total N loss and indirectly measured N loss through a mass balance …

This paper proposes an innovative method for factor analyzing data that potentially contains individual response bias. Past methods include the use of “ipsative” data, or, related to that, “ipsatized” data. Unfortunately, factor analysis as the main method used for analyzing the dimensionality of data, …