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Stratified exercise therapy compared with usual care by physical therapists in patients with knee osteoarthritis: A randomized controlled trial protocol (OCTOPuS study).

J. Knoop; J Dekker; M van der Leeden; M. de Rooij; W.F. Peter; L. van Bodegom-Vos; J.M. van Dongen; N. Lopuhäa; K.L. Bennell; W.F. Lems; M. van der Esch; T.P. Vliet Vlieland; R.W.J.G. Ostelo

OBJECTIVES: Knee osteoarthritis (OA) is characterized by its heterogeneity, with large differences in clinical characteristics between patients. Therefore, a stratified approach to exercise therapy, whereby patients are allocated to homogeneous subgroups and receive a stratified, subgroup-specific intervention, …

2020AlgemeenArtikel

Stratified exercise therapy compared with usual care by physical therapists in patients with knee osteoarthritis

Knoop, Jesper; Dekker, Joost; van der Leeden, Marike; de Rooij, Mariëtte; Peter, Wilfred F. H.; van Bodegom-Vos, Leti; van Dongen, Johanna M; Lopuhäa, Nique; Bennell, Kim L.; Lems, Willem F.; van der Esch, Martin (Centre Of Expertise Urban Vitality); Vliet Vlieland, Thea P.M.; Ostelo, Raymond W.J.G.

2020AlgemeenArtikel

Achieving protein targets without energy overfeeding in critically ill patients: A prospective feasibility study

Looijaard, W. G.P.M.; Denneman, N.; Broens, B.; Girbes, A.R.J.; Weijs, P. J.M. (Lectoraat Voeding En Beweging); Oudemans-van Straaten, H.M.

Background & aims: High protein delivery during early critical illness is associated with lower mortality, while energy overfeeding is associated with higher mortality. Protein-to-energy ratios of traditional enteral formulae are sometimes too low to reach protein targets without energy overfeeding. …

2019-12AlgemeenArtikel

Decision making on (dis)continuation of long-term treatment in mental health services is an interpersonal negotiationrather than an objective process

Bauke Koekkoek; Berno van Meijel (Lector); A. Perquin; G. Hutschemaekers

Background: Research into termination of long-term psychosocial treatment of mental disorders is scarce. Yearly 25% of people in Dutch mental health services receive long-term treatment. They account for many people, contacts, and costs. Although relevant in different health care systems, (dis)continuation …

2019GezondheidArtikel

A prospective international observational prevalence study on prone positioning of ARDS patients

investigators of the APRONET Study Group, the REVA Network, the Réseau recherche de la Société Française d’Anesthésie-Réanimation (SFAR-recherche) and the ESICM Trials Group

INTRODUCTION: While prone positioning (PP) has been shown to improve patient survival in moderate to severe acute respiratory distress syndrome (ARDS) patients, the rate of application of PP in clinical practice still appears low. AIM: This study aimed to determine the prevalence of use of PP in ARDS …

2018-01AlgemeenArtikel

De-implementation strategy to Reduce the Inappropriate use of urinary and intravenous CATheters study protocol for the RICAT-study

Laan, Bart J.; Spijkerman, Ingrid J. B.; Godfried, Mieke H.; Pasmooij, Berend C.; Maaskant, Jolanda M.; Borgert, Marjon J.; Opmeer, Brent C.; Vos, Margreet C.; Geerlings, Suzanne E.

BACKGROUND: Urinary and (peripheral and central) intravenous catheters are widely used in hospitalized patients. However, up to 56% of the catheters do not have an appropriate indication and some serious complications with the use of these catheters can occur. The main objective of our quality improvement …

2017-01-10AlgemeenArtikel

DESTINE. A practice-based intervention to increase empowerment in patients with type 2 diabetes

Esther du Pon (Lid Lectoraat); N. Kleefstra (Onderzoeker); Ad van Dooren (Lector); H.J.G. Bilo (Onderzoeker); A.M. van Dulmen (Onderzoeker)

From the publisher's site: "Trial design: Self-management plays a central role in diabetes management. However, not all patients are able to translate the health care providers’ recommendations for effective self-management in daily life. Diabetes Education and Self-management to Increase Empowerment …

2017GezondheidArtikel

Countering Ransomware Using Anomaly Detection of Endpoint Events

V.A. van der Eijk (Student); H. Vreugth, de (Begeleider); P. Burghouwt (Begeleider)

This research, commissioned by Fox-IT, is focused on the development of a new concept in cybersecurity event monitoring to improve the detection capabilities of the CTM Endpoint Module. Additional background information of Fox-IT is provided in Chapter 2. The description of the research assignment and …

2017ICT & MediaBachelor

Examining the construct and known-group validity of a composite endpoint for The Older Persons and Informal Caregivers Survey Minimum Data Set (TOPICS-MDS); A large-scale data sharing initiative

Hofman, Cynthia S.; Lutomski, Jennifer E.; Boter, Han; Buurman, Bianca M.; de Craen, Anton J. M.; Donders, Rogier; Olde Rikkert, Marcel G. M.; Makai, Peter; Melis, René J. F.

Background Preference-weighted multi-faceted endpoints have the potential to facilitate comparative effectiveness research that incorporates patient preferences. The Older Persons and Informal Caregivers Survey—Composite endpoint (TOPICS-CEP) is potentially a valuable outcome measure for evaluating interventions …

2017AlgemeenArtikel

Do Self-Management Interventions Work in Patients With Heart Failure? An Individual Patient Data Meta-Analysis

Frank Peters-Klimm; Filipe Atienza; Pieta Bruggink-André de la Porte; Rolf H.H. Groenwold; Nini H. Jonkman; Marcia E. Leventhal; Ross T. Tsuyuki; Michael W. Rich; Dirk J.A. Lok; Barbara Riegel; Dirk J. van Veldhuisen; Lynda Blue; Anna Strömberg; Jan Mårtensson; Haruka Otsu; Javier Muñiz; Michele Heisler; Tiny Jaarsma; Heleen Westland; Marieke J. Schuurmans; Jaap C.A. Trappenburg; Arno W. Hoes; Paul L. Hebert; Gertrudis I.J.M. Kempen; Darren A. DeWalt; Susanna Ågren

Background—Self-management interventions are widely implemented in care for patients with heart failure (HF). Trials however show inconsistent results and whether specific patient groups respond differently is unknown. This individual patient data meta-analysis assessed the effectiveness of self-management …

2016-03-22GezondheidArtikel

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