Increasing awareness of the impact of frailty on elderly people resulted in research focusing on factors that contribute to the development and persistence of frailty including nutrition and physical activity. Most effort so far has been spent on understanding the association between protein intake and …

Paul Wagstaff Commemorative Lecture 2019Prof. dr. Hans HobbelenHanze University of Applied Sciences Groningen, the NetherlandsPhysiotherapy and FrailtyFor a physiotherapist it can be difficult to use the term frailty in relation to the physical condition of a patient. We should focus on improvement of …

Frailty is a disputed but important concept in the care of older people. The agreed definition ( Fried et al 2001) is clinically driven and focusses on physical components and incapacity. But frailty is determined not only by disability and comorbidity. How do those defined by others as frail – perceive …

Background: Optimal self-management in kidney transplant recipients is essential for patient and graft survival, reducing comorbidity and health care costs while improving the quality of life. However, there are few effective interventions aimed at providing self-management support after kidney transplantation. Objective: …

OBJECTIVES: To determine the risk of first unplanned all-cause readmission and mortality of patients ≥70 years with acute myocardial infarction (AMI) or heart failure (HF) and to explore which effects of baseline risk factors vary over time. METHODS: A retrospective cohort study was performed on hospital …

In children developmental disorders expresses themselves by a variable presentation of symptoms and frequent manifestation of comorbidity of a complex nature. In addition to the classification of a disorder, individualising diagnostics is a means to realize assessment and treatment that are fine-tuned …

Neurofibromatosis type 1 (NF1) is a neurocutaneous disorder associated with lifelong tumor growth propensity and neurocognitive impairments. Although follow‐up of adults with NF1 often focuses on tumor growth, follow‐up of cognitive or social problems and other NF1‐related comorbidity is often not a …

Purpose : A structured, tailored exercise therapy strategy was found to significantly improve physical functioning, reduce pain and was safe for patients with knee osteoarthritis (OA) and severe comorbidity. The intervention was performed in a specialized, secondary care center. Before the intervention …

Background: Hypothyroidism is a common endocrine disorder and the standard treatment is replacement therapy with levothyroxine (LT4). Although many hypothyroid patients improve upon treatment with LT4, a proportion seems to experience residual hypothyroid complaints despite treatment, even when plasma …

We assessed the value of screening for cognitive abnormalities in a chronically infected HIV population (N = 388) and investigated the association with clinical correlates. The mean age was 48 years (±11), the majority of the patients were male (89%), the median duration of infection was 6 years [interquartile …