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Changes in inflammation and musculoskeletal tissue-derived biomarker serum levels in response to high- and low-intensity resistance training in individuals with knee osteoarthritis

Jansen, N.E.; Engstrøm, A.; Thudium, C.S.; Bay-Jensen, A-C.; de Zwart, A.H.; Dekker, J.; Lems, W.F.; Gerritsen, M.; van Spil, W.E.; Jaspers, R.T.; Turkstra, F.; van der Leeden, M.; van der Esch, M. (Lectoraat Interdisciplinaire Zorg Voor Chronische Gewrichtsaandoeningen)

Purpose: Exercise therapy with a focus on muscle strengthening has proven to be effective for the management of knee osteoarthritis (OA). Yet it is not known whether high-intensity resistance training (RT) is more effective in improving upper leg muscle strength and physical performance than low-intensity …

2020-04AlgemeenArtikel

Doxepin cream is not effective in reducing itch in burn scar patients

Kwa, K A A; Legemate, C M; Pijpe, A; Meij-de Vries, A; Middelkoop, E; van Baar, M E; Breederveld, R S; Nieuwenhuis, M K (Functional Recovery And Quality Of Life After Burns)

OBJECTIVE: To evaluate the effect of doxepin hydrochloride 5% cream on reducing pruritus in burn scar patients compared to a placebo cream. METHOD: We conducted a multicenter triple-blind randomized clinical placebo-controlled crossover trial in which burn patients ≥18 years with an itch intensity ≥3 …

2020-03-01AlgemeenArtikel

The effectiveness of a nurse‐led intervention to support family caregivers in end‐of‐life care: study protocol for a cluster randomized controlled trial

Y.N. Becqué; J.A.C. Rietjens; A. van der Heide; F.E. Witkamp

Aim To evaluate the feasibility of a structured nurse‐led supportive intervention and its effects on family caregivers in end‐of‐life care at home. Background Family caregivers are crucial in end‐of‐life care. They may experience burden due to the responsibilities associated with caregiving. Some family …

2020-02-11GezondheidArtikel

Omega-3 en de mondgezondheid

Thirza Bustraan (Student); Liesbeth Haverkort (Begeleider)

Doel: Een adequate en evenwichtige inname van Omega-3 meervoudige onverzadigde vetzuren (MOV’s) blijkt van belang en gunstig te zijn voor bescherming tegen inflammatie, chronische en metabole ziekten. Het doel van dit onderzoek was het verkrijgen van kennis en inzicht over de invloed van Omega-3 op de …

2020GezondheidBachelor

Completeness of the description of manipulation and mobilisation techniques in randomized controlled trials in neck pain; A review using the TiDieR checklist

Jan Pool (Lid Lectoraat); François Maissan (Lid Lectoraat); Nanna de Waele; Harriët Wittink (Lector); Raymond Ostelo

Study design: A secondary analysis of a systematic review. Background: Manipulations or mobilizations are commonly used interventions in patients with mechanical neck pain. The treatment effects have often been studied in randomized controlled trials (RCT) which are generally considered the gold standard …

2020GezondheidArtikel

Mobile Health App (AGRIPPA) to Prevent Relapse After Successful Interdisciplinary Treatment for Patients With Chronic Pain: Protocol for a Randomized Controlled Trial

Stefan Elbers (Onderzoeker); Jan Pool (Onderzoeker); Harriët Wittink (Lector); Albere Köke (Onderzoeker); Else Scheffer (Onderzoeker); Rob Smeets (Onderzoeker)

Background: To facilitate adherence to adaptive pain management behaviors after interdisciplinary multimodal pain treatment, we developed a mobile health app (AGRIPPA app) that contains two behavior regulation strategies. Objective: The aims of this project are (1) to test the effectiveness of the AGRIPPA …

2020GezondheidArtikel

Indentation marks, skin temperature and comfort of two cervical collars

Jobbe Leenen (Onderzoeker); Wietske Blom-Ham (Onderzoeker); Luke Leenen (Onderzoeker)

Background: Collar-related pressure ulcers (CRPU) are a problem in trauma patients with a suspicion of cervical cord injury patients. Indentation marks (IM), skin temperature (Tsk) and comfort could play a role in the development of CRPU. Two comparable cervical collars are the Stifneck® and Philadelphia®. …

2020GezondheidArtikel

The effect of nutritional counseling on muscle mass and treatment outcome in patients with metastatic colorectal cancer undergoing chemotherapy: A randomized controlled trial

A. van der Werf; J.A.E. Langius; A Beeker; AJ ten Tije; AJ Vulink; A Haringhuizen; J Berkhof; HJ van der Vliet; H.M.W. Verheul; Marian de van der Schueren

Background & aims: A low muscle mass before start of treatment and loss of muscle mass during chemotherapy is related to adverse outcomes in patients with cancer. In this randomized controlled trial, the effect of nutritional counseling on change in muscle mass and treatment outcome in patients with …

2020AlgemeenArtikel

Stratified exercise therapy compared with usual care by physical therapists in patients with knee osteoarthritis: A randomized controlled trial protocol (OCTOPuS study).

J. Knoop; J Dekker; M van der Leeden; M. de Rooij; W.F. Peter; L. van Bodegom-Vos; J.M. van Dongen; N. Lopuhäa; K.L. Bennell; W.F. Lems; M. van der Esch; T.P. Vliet Vlieland; R.W.J.G. Ostelo

OBJECTIVES: Knee osteoarthritis (OA) is characterized by its heterogeneity, with large differences in clinical characteristics between patients. Therefore, a stratified approach to exercise therapy, whereby patients are allocated to homogeneous subgroups and receive a stratified, subgroup-specific intervention, …

2020AlgemeenArtikel

Stratified exercise therapy compared with usual care by physical therapists in patients with knee osteoarthritis

Knoop, Jesper; Dekker, Joost; van der Leeden, Marike; de Rooij, Mariëtte; Peter, Wilfred F. H.; van Bodegom-Vos, Leti; van Dongen, Johanna M; Lopuhäa, Nique; Bennell, Kim L.; Lems, Willem F.; van der Esch, Martin (Centre Of Expertise Urban Vitality); Vliet Vlieland, Thea P.M.; Ostelo, Raymond W.J.G.

2020AlgemeenArtikel

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