OBJECTIVE: The World Health Organization (WHO) recently proposed an Integrated Care for Older People approach to guide health systems and services in better supporting functional ability of older people. A knowledge gap remains in the key elements of integrated care approaches used in health and social …

INTRODUCTION: Minerals may contribute to prevent and treat sarcopenia, the age-related loss of muscle mass, muscle strength, and physical performance. So far, there is no comprehensive review on the impact of minerals on sarcopenia outcomes. The aim of this systematic review is to evaluate the role of …

Accurate assessment of TP53 gene status in sporadic tumors and in the germline of individuals at high risk of cancer due to Li–Fraumeni Syndrome (LFS) has important clinical implications for diagnosis, surveillance, and therapy. Genomic data from more than 20,000 cancer genomes provide a wealth of information …

BACKGROUND: People with intellectual disabilities (ID) experience more health problems and have different lifestyle change needs, compared with the general population. AIMS: To improve lifestyle change interventions for people with ID, this review examined how behaviour change techniques (BCTs) were …

AimTo assess the quality of evidence and determine the effect of patient-related and economic outcomes of self-management support interventions in chronically ill patients with a low socio-economic status. BackgroundIntegrated evidence on self-management support interventions in chronically ill people …

Standing up is harder to perform when getting older. The company SillaPlus want to create a physical device that can be attached to already existing chairs and will help elderly people get up from a chair. The company reached out to students who want to help with the development of a get up aid. The …

Numerous databases containing information about DNA, RNA, and protein variations are available. Gene‐specific variant databases (locus‐specific variation databases, LSDBs) are typically curated and maintained for single genes or groups of genes for a certain disease(s). These databases are widely considered …

BACKGROUND: Critical illness and the problems faced after ICU discharge do not only affect the patient, it also negatively impacts patients' informal caregivers. There is no review which summarizes all types of burden reported in informal caregivers of ICU survivors. It is important that the burdens …

Objectives: To systematically review interventions that aim to improve the governance of patient safety within emergency care on effectiveness, reliability, validity and feasibility. Design: A systematic review of the literature. Methods: PubMed, EMBASE, Cumulative Index to Nursing and Allied Health …

Abstract Problem definition. Chronic diseases are accountable for the leading cause of mortality on the globe. Non-communicable disease (NCD) – a type of chronic illness – causes burden on multiple levels, ranging from personal to economical strain, resulting in immense number deaths annually. Dominant causes …