Aims Genetic hypertrophic cardiomyopathy (HCM) is caused by mutations in sarcomere protein-encoding genes (i.e. genotype-positive HCM). In an increasing number of patients, HCM occurs in the absence of a mutation (i.e. genotype-negative HCM). Mitochondrial dysfunction is thought to be a key driver of …

Vragen of, en onder welke voorwaarden, persoonsgegevens gedeeld kunnen worden in samenwerking tussen professionals, leidt tot dilemma's voor gedragwetenschappers. In dit artikel wordt de relatie tussen de beroepscodes en de AVG geduid. Vaak zal de beroepscode leidend zijn voor orthopedagogen en psychologen. …

We describe here the design and implementation of the Fashion Tech Farm (FTF), which aims to drive sustainable innovation in garments and fashion. We describe our goals, design principles, and the implementation. The design principles are rooted in an understanding of the fashion system, open networks, …

In 2007 vond een opgraving plaats van de beerkelder S1 in het pand Vaaltstraat 4 te Zutphen. De opgraving is uitgevoerd door het team archeologie van de gemeente Zutphen. Het kwetsbare afval dat is aangetroffen in de beerkelder, moest worden opgegraven omdat de beerkelder ten gevolge van de verbouwing …

Dit stappenplan helpt docententeams om stapsgewijs en evidence-informed te verbeteren. Het vormgeven van je onderwijs volgens de principes van blended learning heeft vele voordelen voor zowel student als docent. Dit vraagt echter om een grondig herontwerp van jouw onderwijs. Omdat er soms op korte termijn …

This roadmap helps teacher teams to improve their education step-by-step in an evidence-informed manner. Shaping your education using the principles of blended learning has many advantages for both students and teachers. However, this requires a thorough, long-term redesign of courses. Partly due to …

Airport infrastructure evolves alongside legacy systems and processes that limits the ability to fully realise the efficiency potential of costly renovations. Airports will continue to take advantage of current and future technologies. Nevertheless, for such systems to work as efficiently as possible, …

Background: Burden of disease estimates are an important resource in public health. Currently, robust estimates are not available for the burn population. Our objectives are to adapt a refined methodology (INTEGRIS method) to burns and to apply this new INTEGRIS-burns method to estimate, and compare, …

Robotic services, which have started to appear in urban environments, are going to transform our society. Designers of these robots are not only required to meet technical and legal challenges, but also address the potential social, political, and ethical consequences of their design choices. In this …