Both because of the shortcomings of existing risk assessment methodologies, as well as newly available tools to predict hazard and risk with machine learning approaches, there has been an emerging emphasis on probabilistic risk assessment. Increasingly sophisticated AI models can be applied to a plethora …

While the original definition of replacement focuses on the replacement of the use of animals in science, a more contemporary definition focuses on accelerating the development and use of predictive and robust models, based on the latest science and technologies, to address scientific questions without …

To study the ways in which compounds can induce adverse effects, toxicologists have been constructing Adverse Outcome Pathways (AOPs). An AOP can be considered as a pragmatic tool to capture and visualize mechanisms underlying different types of toxicity inflicted by any kind of stressor, and describes …

Dit artikel gaat over de mogelijke introductie van micro-aardappelen, ofwel microtubers, op de Europese markt en de uitdagingen met betrekking tot alkaloïden. Aardappelen zijn wereldwijd essentieel voor voedselzekerheid, maar microtubers, kleine aardappelknollen, blijven relatief onbekend. Nederlandse …

Een stripboek helemaal gewijd aan de veldboon! Waarom? In het project Bean me up! is drie jaar onderzoek gedaan naar de vraag: kan de Nederlandse veldboon als eiwitbron de soja uit verre landen vervangen? Is de Nederlandse veldboon geschikt om te verwerken in voedingsmiddelen? De resultaten zijn veelbelovend! …

Objective To develop and internally validate a prognostic model to predict chronic pain after a new episode of acute or subacute non-specific idiopathic, non-traumatic neck pain in patients presenting to physiotherapy primary care, emphasising modifiable biomedical, psychological and social factors. Design …

Communities worldwide are critically re-examining their seasonal cultures and calendars. As cultural frameworks, seasons have long patterned community life and provided repertoires for living by annual rhythms. In a chaotic world, the seasons - winter, the monsoon and so on - can feel like stable cultural …

Arrhythmogenic Cardiomyopathy (ACM), also known as arrhythmogenic right ventricular cardiomyopathy/dysplasia (ARVC/D) is a rare hereditary disease of the heart, where the connective, and fatty tissue is deposited in the muscle tissue of the ventricular myocardium primarily of the right but also left …

Deepfake videos are defined as a resulting media from the synthesis of different persons images and videos, mostly faces, replacing a real one. The easy spread of such videos leads to elevated misinformation and represents a threat to society and democracy today. The present study aims to collect and …

Metaverse, a burgeoning technological trend that combines virtual and augmented reality, provides users with a fully digital environment where they can assume a virtual identity through a digital avatar and interact with others as they were in the real world. Its applications span diverse domains such …