Ubiquitin (Ub) is a protein which post-translationally modifies other proteins (its target substrates) and determines their cellular fate. Ub can label substrates for degradation, it can also alter the location of their substrates within a cell or even affect their activity. Chains can be formed via …

BACKGROUND:Reintroduction of a food after negative food challenge (FC) faces many obstacles. There are no studies available about this subject in adults.OBJECTIVE:To investigate the frequency, reasons and risk factors of reintroduction failure in adults.METHODS:In this prospective study, adult patients …

Non-ballistic hypersonic missiles are highly manoeuvrable weapons that move with a speed of Mach 5 or more. Russia, China, and the US are the frontrunners in developing those weapons. The combination of speed, accuracy, manoeuvrability, and range makes hypersonic missiles effective both against time-sensitive …

Russian disinformation has thus far proven to be unconvincing for most Dutch target audiences. This is the conclusion of the present chapter. Information and disinformation have become effective weapons in international politics. This is part of a development where the weapons and concepts used in deterrence …

The second Workshop on Tradeoffs Scenarios between the Impact on Seafloor Habitats and Provisions of catch/value (WKTRADE2) was established to provide input on trade-offs aspects to the Working group on Fisheries Benthic Impact and Trade-offs (WGFBIT). As such, the workshop was tasked to: 1) demonstrate …

Herein, Zeolitic imidazolate framework-8 (ZIF-8) is considered as an easy and cheap to prepare alternative catalyst for the isomerization of glucose and production of 5-hydroxymethyl furfural (HMF). For the synthesis of the ZIF-8 catalysts two preparation methods were evaluated, being room temperature …

The experimental fishing method of pulse trawling was initially developed to decrease fuel consumption rates of flatfish fisheries in the North Sea targeting common sole (Solea solea). By replacing tickler chains with electrodes, the targeted fish is immobilised until it enters the net by using electrical …

In the search for low greenhouse gas propulsion, the dual fuel engine provides a solution to use low carbon fuel at diesel-like high efficiency. Also a lower emission of NOx and particles can be achieved by replacing a substantial part of the diesel fuel by for example natural gas. Limitations can be …

The purpose of this thesis is to investigate the policy changes that Italy and the European Union (EU) experienced due to the EU migrant crisis. The European country that, besides Greece and Spain, has been most affected by problems of irregular migrant arrivals by the Mediterranean Sea, is Italy. The …