Owing to the non-toxic, nonimmunogenic effects and high affinity to specific molecules, some single-stranded oligonucleotides, namely aptamers, can be exploited in biochemical applications to deliver bioactive elements and interact with the desired targets. Among many identified aptamers, D#7 was utilized …

This ‘cohort profile’ aims to provide a description of the study design, methodology, and baseline characteristics of the participants in the Corona Behavioral Unit cohort. This cohort was established in response to the COVID-19 pandemic by the Dutch National Institute for Public Health and the Environment …

Young widowhood, conceptualized as the loss of one’s spouse before the age of 50, is a profoundly painful and distressing loss (Den Elzen, 2017, 2018). The literature on young widowhood shows the death of a partner generally causes a fragmentation of the self, as it violates expectations of the normal …

Underutilised charging stations can be a bottleneck in the swift transition to electric mobility. This study is the first to research cooperative behaviour at public charging stations as a way to address improved usage of public charging stations. It does so by viewing public charging stations as a common-pool …

Tumor necrosis factor alpha (TNF-α) and its key role in modulating immune responses has been widely recognized as a therapeutic target for inflammatory and neurodegenerative diseases. Even though inhibition of TNF-α is beneficial for the treatment of certain inflammatory diseases, total neutralization …

Purpose This study aims to qualitatively examine the relationship between the indoor environmental quality (IEQ), lecturers’ and students’ perceived internal responses and academic performance. Design/methodology/approach To capture user experiences with the IEQ in classrooms, semi-structured interviews …

Since the return of the grey wolf (Canis lupus) in the Netherlands in 2015, much research has been done on the ecology and distribution of the species. This has led to a dietary study using hair- and DNA-sampling of wolf scats, and preliminary analyses of DNA in wolf scats showed that DNA from non-prey, …

We aim to understand how actors respond to field logic plurality and maintain legitimacy through business model innovation. Drawing on a longitudinal field study in the fashion industry, we traced how de novo and incumbent firms incorporate circular logics in business models (for sustainability) and …

The prevention and diagnosis of frailty syndrome (FS) in cardiac patients requires innovative systems to support medical personnel, patient adherence, and self-care behavior. To do so, modern medicine uses a supervised machine learning approach (ML) to study the psychosocial domains of frailty in cardiac …

There is an increasing interest in how to create an effective and comfortable indoor environment for lecturers and students in higher education. To achieve evidence-based improvements in the indoor environmental quality (IEQ) of higher education learning environments, this research aimed to gain new …