The search for existing non-animal alternative methods for use in experiments is currently challenging because of the lack of both comprehensive structured databases and balanced keyword-based search strategies to mine unstructured textual databases. In this paper we describe 3Ranker, which is a fast, …

Background: Innovative technologies such as game consoles and smart toys used with games or playful approaches have proven to be successful and attractive in providing effective and motivating hand therapy for children with cerebral palsy (CP). Thus, there is an increased interest in designing and implementing …

Innovation in the 21st century has been moving continuously away from the model embraced in the last century, which was characterized as a profit-oriented and silo-targeted one. Currently, the logic is being driven towards “the social” sense and value of the transformation within the reality of complexity …

Abstract Background Clients with severe mental illness (SMI) have overall poor physical health. SMI reduces life expectancy by 5–17 years, primarily due to physical comorbidity linked to cardiometabolic risks that are mainly driven by unhealthy lifestyle behaviours. To improve physical health in clients …

Patients who are critically ill and receiving invasivemechanical ventilation are at increased risk for accumula-tion of secretions in the lower airways. Such accumula-tion of airway mucus can induce atelectasis and contributeto ventilator-associated pneumonia. Preventive airwaycare interventions, including …

Built environments are increasingly vulnerable to the impacts of climate change. Most European towns and cities have developed horizontally over time but are currently in the process of further densification. High-rise developments are being built within city boundaries at an unprecedented rate to accommodate …

Patients on general wards are at risk of complications, often associated with deviations in vital signs. Unfortunately, the currently used manual method of intermittently measuring vital signs is not optimal, potentially leading to late recognition and treatment of complications, and sometimes with serious …

As fuel is expensive and profit must be maximized, it is wise for the maritime industry to invest in fuel saving applications. One of the possibilities is to replace old turbochargers by new fuel saving ones on the already installed engines, recommended by Wärtsilä. Although the potential fuel savings …

The built environment requires energy-flexible buildings to reduce energy peak loads and to maximize the use of (decentralized) renewable energy sources. The challenge is to arrive at smart control strategies that respond to the increasing variations in both the energy demand as well as the variable …

Plastic pollution of rivers, seas, and oceans is currently one of the most pressing environmental issues. The litter traps constructed by CLEAR RIVERS provide a way to clean the rivers of litter by utilising winds and currents. CLEAR RIVERS wants to know how to improve the effectiveness of current litter …