Epithelial ovarian cancer (EOC) has a poor prognosis in advanced stages. High-dose chemotherapy (HDC) was pursued in the 1990s but was not found to improve survival of patients with EOC in larger studies. Many patients with cancer use Viscum album extracts (VAE). Also called European mistletoe, Viscum …

OBJECTIVES: To compare low contrast detail (LCD) detectability and radiation dose for routine paediatric chest X-ray (CXR) imaging protocols among various hospitals. METHODS: CDRAD 2.0 phantom and medical grade polymethyl methacrylate (PMMA) slabs were used to simulate the chest region of four different …

Lasiocarpine and riddelliine are pyrrolizidine alkaloids (PAs) known to cause liver toxicity. The aim of this study was to predict the inter-species and inter-ethnic human differences in acute liver toxicity of lasiocarpine and riddelliine using physiologically based kinetic (PBK) modelling based reverse …

Van der Burg's study delved into the potential connection between overall survival and patient characteristics, along with radiation dose to the body in lung cancer patients undergoing various treatment schedules. In conclusion, patient characteristics and radiomics data exhibit predictive values for …

Röntgenstraling kan zorgen voor schade aan desoxyribonucleïnezuurmoleculen in het lichaam. De medische stralingsbelasting, mede veroorzaakt door interventies waarbij röntgendoorlichting gebruikt wordt, levert een substantiële bijdrage aan de totaaldosis waaraan een persoon gemiddeld blootstaat. Bij anesthesiologische …

Abstract Background: We studied the relationship between trismus (maximum interincisor opening [MIO] ≤35 mm) and the dose to the ipsilateral masseter muscle (iMM) and ipsilateral medial pterygoid muscle (iMPM). Methods: Pretreatment and post-treatment measurement of MIO at 13 weeks revealed 17% of …

a b s t r a c t: Objective: To study the impact of target volume changes in brain metastases during fractionated stereotactic radiosurgery (fSRS) and identify patients that benefit from MRI guidance. Material and methods: For 15 patients (18 lesions) receiving fSRS only (fSRSonly) and 19 patients (20 …

The effect and methods of changing the norepinephrine syringe on the Intensive Care Unit: a quantitative, observational pilot study BACKGROUND - The change of a syringe with noradrenalin (NOR) often causes fluctuations in the blood pressure. This nursing intervention occurs often at the Intensive Care …

Reply to ‘Comment on ‘Use of an in vitro–in silico testing strategy to predict inter-species and inter-ethnic human diferences in liver toxicity of the pyrrolizidine alkaloids lasiocarpine and riddelliine’ by Ning et al., Arch Toxicol doi: https://doi.org/10.1007/s00204-019-02397-7’, Arch Toxicol doi: …

INAUGURAL LECTURE The world is in disarray. Species are extinct, climates are changing, we are becoming unhealthier. To liberate ourselves from this doom scenario we need to take care of ourselves and our environment. The solutions of former generations offer no future solace. Moreover, these caused …