Van Burken and Royakkers address the question 'who is responsible and in what way?' with regard to one of the contemporary developments in an ICT-setting on the battlefield: the battlefield super soldier suit (BSSS). This suit was developed to enhance the survival chance of soldiers on the battlefield. …

Atrial fibrillation (AF) is the most common clinical tachyarrhythmia associated with significant morbidity and mortality and is expected to affect approximately 30 million North Americans and Europeans by 2050. AF is a persistent disease, caused by progressive, often age-related, derailment of proteostasis …

Hoofdstuk in Progression in forensic Psychiatry: About Boundaries van prof. mr. Marc Groenhuijsen en prof. dr. T.I. Oei. As a young adolescent the man started using soft drugs and as a result was expelled from school. Following a registration with RIAGG he was placed in a children’s home for some years. …

Falls are a major health problem in nursing home residents with dementia. In nursing homes one-third of all falls results in an injury. In order to take tailor-made preventive measures in time, the fall risk profile of each individual nursing home resident should be periodically evaluated. A systematic …

Glucocorticoids (GCs), such as prednisolone (PRED), are widely prescribed anti-inflammatory drugs, but their use may induce glucose intolerance and diabetes. GC-induced beta cell dysfunction contributes to these diabetogenic effects through mechanisms that remain to be elucidated. In this study, we hypothesized …

BACKGROUND: Prednisolone and other glucocorticoids (GCs) are potent anti-inflammatory and immunosuppressive drugs. However, prolonged use at a medium or high dose is hampered by side effects of which the metabolic side effects are most evident. Relatively little is known about their effect on gene-expression …

The scientific literature represents a rich source for retrieval of knowledge on associations between biomedical concepts such as genes, diseases and cellular processes. A commonly used method to establish relationships between biomedical concepts from literature is co-occurrence. Apart from its use …

Background: Falls are a major health problem among the elderly, particularly in nursing homes. Abnormalities of balance and gait, psychoactive drug use, and dementia have been shown to contribute to fall risk. Methods: We conducted a systematic review of the literature to investigate which psychoactive …

Er is een literatuur onderzoek gedaan in opdracht van het Medisch Trainingscentrum Geldrop. Dit onderzoek is gedaan naar de betrouwbaarheid, validiteit en bruikbaarheid van testen die het aërobe vermogen bepalen bij personen die bètablokkers gebruiken. Bètablokkers onderdrukken de hartfrequentie. Daardoor …