New approach methodologies predicting human cardiotoxicity are of interest to support or even replace in vivo-based drug safety testing. The present study presents an in vitro–in silico approach to predict the effect of inter-individual and inter-ethnic kinetic variations in the cardiotoxicity of R- …

Standard SARS-CoV-2 testing protocols using nasopharyngeal/throat (NP/T) swabs are invasive and require trained medical staff for reliable sampling. In addition, it has been shown that PCR is more sensitive as compared to antigen-based tests. Here we describe the analytical and clinical evaluation of …

Green roofs received increased scientific attention with respect to climate adaptation in urban environments for their hydrological, biodiversity and insulative capacities. Yet, the thermal properties of roofs with an additional water layer underneath the vegetation substrate (blue-green roofs) are not …

The ‘What Being the Parent of a New Baby is Like-Revised’ (WPL-R) is an instrument designed to measure adaptation to parenthood. In the process of pilot testing and validating the WPL-R in a postpartum Dutch population, we became aware of the potentially sensitive nature of the measure. Despite the ethics …

In current nature valuation efforts, sociocultural values are often overlooked. Calls for the importance of including these values often advise to use a mixed-method approach; however, restrictions concerning budget and time often prevent researchers from doing so. In this study we offer a compromise—a …

The present study compares two approaches to evaluate the effects of inter-individual differences in the biotransformation of chlorpyrifos (CPF) on the sensitivity towards in vivo red blood cell (RBC) acetylcholinesterase (AChE) inhibition and to calculate a chemical-specific adjustment factor (CSAF) …

Stormwater runoff can contain high amounts of Potential Toxic Elements (PTE) as heavy metals. PTE can have negative and direct impact on the quality of surface waters and groundwater. The European Water Framework Directive (WFD) demands enhanced protection of the aquatic environment. As a consequence, …

Social robots are reported to hold great potential for education. However, both scholars and key stakeholders worry about children’s social-emotional development being compromised. In aiming to provide new insights into the impact that social robots can have on the social-emotional development of children, …

Digital innovation in education – as in any other sector – is not only about developing and implementing novel ideas, but also about having these ideas effectively used as well as widely accepted and adopted, so that many students can benefit from innovations improving education. Effectiveness, transferability …

Extensive research has explored the role of perfectionism in individuals (Hewitt & Flett, 1991; Mackinnon & Sherry, 2012). Perfectionism is considered as a stable personality trait that is characterized by “high standards of performance which are accompanied by tendencies for overly critical evaluations …