In the four studies comprising this dissertation, we aim to shed more light on the role of implementation quality of FLPs. In the first study, we reviewed the literature on implementation quality of FLPs, to gain insight into how implementation has been assessed in studies so far, what previous studies …

The critical care community still has mixed feelings when considering the optimal nutrition of intensive care unit (ICU) patients, which is understandable as randomized controlled trials have not been very helpful in improving clinical practice. There have been no randomized controlled trials (RCTs) …

Background: Medically unexplained physical symptoms are an important health problem in primary care, with a spectrum from mild to chronic. The burden of chronic medically unexplained physical symptoms is substantial for patients, health care professionals, and society. Therefore, early identification …

Background: A pragmatic, stepped wedge trial design can be an appealing design to evaluate complex interventions in real-life settings. However, there are certain pitfalls that need to be considered. This paper reports on the experiences and lessons learned from the conduct of a cluster randomized, …

Background: In addition to medical intervention and counseling, patients with cardiovascular disease (CVD) need to manage their disease and its consequences by themselves in daily life. Objective: The aim of this paper is to describe the development of "Vascular View," a comprehensive, multi-component, …

Following the withdrawal of large scale military contingents from Afghanistan and Iraq, enthusiasm in the Western world for what has been called armed state-building seems to have sunk to an all-time low. This is not entirely surprising given the high stakes and the meagre results of the massive efforts …

Following on from successful early intervention programs abroad, the Netherlands also introduced a number of different programs to tackle educational disadvantage in preschool and early years education. Studies that investigate the effects of Dutch early childhood interventions have been published since …

In a continuation of a prospective longitudinal cohort study in a healthy population on the course of skull shape from birth to 24 months, at 5 years of age, 248 children participated in a follow-up assessment using plagiocephalometry (ODDI-oblique diameter difference index, CPI-cranio proportional index). …

SAMENVATTING Dit onderzoeksrapport geeft antwoord op de centrale vraag: ‘Welke rol speelt de gemeente Amsterdam bij het proces van gentrificatie in haar stad?’ De aanleiding voor dit onderzoek ligt in het feit dat gentrificatie een veelbesproken thema is, maar binnen het debat veel onduidelijkheid bestaat …

Background: Screening and brief interventions (SBI) in primary healthcare are cost-effective in risky drinkers, yet they are not offered to all eligible patients. This qualitative study aimed to provide more insight into the factors and mechanisms of why, how, for whom and under what circumstances implementation …