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Mapping ongoing nutrition intervention trials in muscle, sarcopenia, and cachexia: a scoping review of future research.

C.E. Orsso; M. Montes-Ibarra; M Findlay; Barbara van der Meij; Marian de van der Schueren; F. Landi; A. Laviano; C.M. Prado

Muscle loss alone, or in the context of sarcopenia or cachexia, is a prevalent condition and a predictor of negative outcomes in aging and disease. As adequate nutrition is essential for muscle maintenance, a growing number of studies has been conducted to explore the role of specific nutrients on muscle …

2022AlgemeenArtikel

Comparison of the prevalence of 21 GLIM phenotypic and etiologic criteria combinations and association with 30-day outcomes in people with cancer: A retrospective observational study.

N Kiss; B. Steer; J Loeliger; R. Alizadehsani; L. Edbrooke; I Deftereos; E. Laing; A. Khosravi; Marian de van der Schueren

BACKGROUND & AIMS: The Global Leadership Initiative on Malnutrition (GLIM) criteria require validation in various clinical populations. This study determined the prevalence of malnutrition in people with cancer using all possible diagnostic combinations of GLIM etiologic and phenotypic criteria and determined …

2022AlgemeenArtikel

Repeated-Dose Toxicity, Biodistribution, and Shedding Assessments With a ChAd155 Respiratory Syncytial Virus Vaccine Candidate Evaluated in Rabbits and Rats

AH Stokes; C Planty; J Pion; P Ancian; A Rogue; C Bansard; J Silvano; D Papineau; N Ben Abdeljelil; G Maruggi; HF Song; C Spickler; K Blouin; G Dubois; LA Rodriguez; J Baumeister; AM Steff; E Destexhe

Respiratory syncytial virus (RSV) is a leading cause of acute lower respiratory tract infections (LRTI) in infants, and toddlers and vaccines are not yet available. A pediatric RSV vaccine (ChAd155-RSV) is being developed to protect infants against RSV disease. The ChAd155-RSV vaccine consists of a recombinant …

2022AlgemeenArtikel

Predicting readiness for return to sport and performance after anterior cruciate ligament reconstruction rehabilitation.

Inge van Haren; R.E.H. van Cingel; A.L.M. Verbeek; N. van Melick; J.H. Stubbe; H. Bloo; J.H.M.M. Groenewoud; P.J. van der Wees; Bart Staal

BACKGROUND: Determining readiness to return to sport after anterior cruciate ligament (ACL) reconstruction is challenging. OBJECTIVES: To develop models to predict initial (directly after rehabilitation) and sustainable (one year after rehabilitation) return to sport and performance in individuals after …

2022AlgemeenArtikel

Behavioural Interventions in People with Oropharyngeal Dysphagia: A Systematic Review and Meta-Analysis of Randomised Clinical Trials.

R. Speyer; R. Cordier; A.L. Sutt; Lianne Remijn; B.J. Heijnen; M. Balaguer; T. Pommée; M. McInerney; L. Bergström

OBJECTIVE: To determine the effects of behavioural interventions in people with oropharyngeal dysphagia. METHODS: Systematic literature searches were conducted to retrieve randomized controlled trials in four different databases (CINAHL, Embase, PsycINFO, and PubMed). The methodological quality of eligible …

2022AlgemeenArtikel

No evidence for stratified exercise therapy being cost-effective compared to usual exercise therapy in patients with knee osteoarthritis: Economic evaluation alongside cluster randomized controlled trial.

J. Knoop; J. Esser; J Dekker; J.W. de Joode; R.W.J.G. Ostelo; J.M. van Dongen

BACKGROUND: A stratified approach to exercise therapy may yield superior clinical and economic outcomes, given the large heterogeneity of individuals with knee osteoarthritis (OA). OBJECTIVE: To evaluate the cost-effectiveness during a 12-month follow-up of a model of stratified exercise therapy compared …

2022AlgemeenArtikel

Stratified exercise therapy does not improve outcomes compared with usual exercise therapy in people with knee osteoarthritis (OCTOPuS study): a cluster randomised trial.

J. Knoop; J Dekker; J.M. van Dongen; M van der Leeden; M. de Rooij; W.F. Peter; W. de Joode; L. van Bodegom-Vos; N. Lopuhaä; K.L. Bennell; W.F. Lems; M. van der Esch; T.P. Vliet Vlieland; R.W.J.G. Ostelo

QUESTION: In people with knee osteoarthritis, how much more effective is stratified exercise therapy that distinguishes three subgroups (high muscle strength subgroup, low muscle strength subgroup, obesity subgroup) in reducing knee pain and improving physical function than usual exercise therapy? DESIGN: …

2022AlgemeenArtikel

Patients' and clinicians' experiences with stratified exercise therapy in knee osteoarthritis: a qualitative study.

J. Knoop; J.W. de Joode; H. Brandt; J Dekker; R.W.J.G. Ostelo

BACKGROUND: We have developed a model of stratified exercise therapy that distinguishes three knee osteoarthritis (OA) subgroups ('high muscle strength subgroup', 'low muscle strength subgroup', 'obesity subgroup'), which are provided subgroup-specific exercise therapy (supplemented by a dietary intervention …

2022AlgemeenArtikel

Physical activity as a risk or protective factor for falls and fall-related fractures in non-frail and frail older adults: a longitudinal study

van Gameren, Maaike; Hoogendijk, Emiel O.; van Schoor, Natasja M.; Bossen, Daniël (Lectoraat Oefentherapie); Visser, Bart (Centre Of Expertise Urban Vitality); Bosmans, Judith E.; Pijnappels, Mirjam

BACKGROUND: Physical activity may be both a risk and protective factor for falls and fall-related fractures. Despite its positive effects on muscle and bone health, physical activity also increases exposure to situations where falls and fractures occur. This paradox could possibly be explained by frailty …

2022AlgemeenArtikel

Does muscle mass measured with Computed Tomography analysis differ in patients with different types of cancer?

Sealy, Martine (Malnutrition And Healthy Ageing); Van den Broeck, Jona; Brussaard, Carola; Scafoglieri, Aldo; Jager-Wittenaar, Harriët (Malnutrition And Healthy Ageing)

Rationale: Patients with cancer of the upper gastrointestinal tract or lung are more likely to present with malnutrition at diagnosis than, for instance, patients with melanoma. Low muscle mass is an indicator of malnutrition and can be determined by computed tomography (CT) analysis of the skeletal …

2021-12-01AlgemeenConferentiebijdrage

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