In this case study, we want to gain insight into how residents of three municipalities communicate about the new murder scenario of the cold case of Marianne Vaatstra and the possibility of a large-scale DNA familial searching. We investigate how stakeholders shape their arguments in conversation with …

Glucocorticoids (GCs) such as prednisolone are potent immunosuppressive drugs but suffer from severe adverse effects, including the induction of insulin resistance. Therefore, development of so-called Selective Glucocorticoid Receptor Modulators (SGRM) is highly desirable. Here we describe a non-steroidal …

Objective: Balance of prognostic factors between treatment groups is desirable because it improves the accuracy, precision, and credibility of the results. In cluster-controlled trials, imbalance can easily occur by chance when the number of cluster is small. If all clusters are known at the start of …

In order to support aging in place, Dutch elderly that cannot live at home any longer are housed in Assisted Living Facilities (ALF’s). Here they live as independently as possible and can rely on care and services 24 hours a day. Nowadays the intended home-like atmosphere is threatened by the increasing …

In order to be able to age in place, Dutch elderly are being housed in Assisted Living Facilities (ALFs) for over 25 years. Here they can live independently and rely on care and services. The physical scale of ALFs ranges from 30 up to 300 residents. This paper presents the findings of a multiple case …

The past century has been a century characterized by human suffering and conflict. The establishment of the United Nations in the aftermath of World War II has brought the pressing issue of human rights to the attention of the international world. However, the UN’s reluctance to act on occasions of …

This thesis explores the subject of alumni relations with the aim of demonstrating how alumni relations can be of benefit to universities. It also goes into the difficulties that could present themselves with alumni relations both in the shorter and the longer term. This is supported by the testimony …

Formal diplomas and certificates have been accepted as proof that students may receive exemption for parts of their educational programme. Nowadays, though, it is socially desirable that informal and non-formal learning experiences are also recognised. Assessment of prior learning (APL) addresses this …

Penicillin acylase (PA) from Escherichia coli can catalyze the coupling of an acyl group to penicillin- and cephalosporin-derived beta-lactam nuclei, a conversion that can be used for the industrial synthesis of beta-lactam antibiotics. The modest synthetic properties of the wild-type enzyme make it …