BACKGROUND: Chest physiotherapy is widely used in people with cystic fibrosis in order to clear mucus from the airways. OBJECTIVES: To determine the effectiveness and acceptability of chest physiotherapy compared to no treatment or spontaneous cough alone to improve mucus clearance in cystic fibrosis. …

Phytophthora infestans, the causal agent of late blight, remains the main threat to potato production worldwide. Screening of 19 accessions of Solanum dulcamara with P. infestans isolate Ipo82001 in detached leaf assays revealed strong resistance in an individual belonging to accession A54750069-1. This …

The worldwide obesity epidemic is a major and complex problem, resulting from the interaction of individual metabolic, genetic, and psychological factors with meso- and macro environmental factors. Adolescents, with their rapid changes in body composition, together with their shift in orientation from …

This paper presents a multidisciplinary conceptual framework which proposes the symbolic-based eco-genetic process for dealing with complex patterns characterized by multilevel and fuzzy territorial governance, and interrelatedness between the physical world and the symbolic and socially-culturally constructed …

The number of weaned piglets per sow per year is an important parameter for the productivity of sows in pig production. This number depends on several parameters of which in many cases the sow has a central role. To improve the sow’s reproduction it is important to keep the sow’s body condition optimal. …

Phylogenetic patterns show the presence or absence of certain genes in a set of full genomes derived from different species. They can also be used to determine sets of genes that occur only in certain evolutionary branches. Previously, we presented a database named PhyloPat which allows the complete …

Penicillin acylase (PA) from Escherichia coli can catalyze the coupling of an acyl group to penicillin- and cephalosporin-derived beta-lactam nuclei, a conversion that can be used for the industrial synthesis of beta-lactam antibiotics. The modest synthetic properties of the wild-type enzyme make it …

Introduction: To reduce continuously increasing costs in drug development, adverse effects of drugs need to be detected as early as possible in the process. In recent years, compound-induced gene expression profiling methodologies have been developed to assess compound toxicity, including Gene Ontology …