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Repeated-Dose Toxicity, Biodistribution, and Shedding Assessments With a ChAd155 Respiratory Syncytial Virus Vaccine Candidate Evaluated in Rabbits and Rats

AH Stokes; C Planty; J Pion; P Ancian; A Rogue; C Bansard; J Silvano; D Papineau; N Ben Abdeljelil; G Maruggi; HF Song; C Spickler; K Blouin; G Dubois; LA Rodriguez; J Baumeister; AM Steff; E Destexhe

Respiratory syncytial virus (RSV) is a leading cause of acute lower respiratory tract infections (LRTI) in infants, and toddlers and vaccines are not yet available. A pediatric RSV vaccine (ChAd155-RSV) is being developed to protect infants against RSV disease. The ChAd155-RSV vaccine consists of a recombinant …

2022AlgemeenArtikel

Learning and Knowledge Transfer of Professionals within the Building Services Sector

L.C.M. (Laure) Itard (Lector); Marcus Specht (Onderzoeker); E. (Ellen) Sjoer (Lector); Wim Zeiler (Onderzoeker)

Buildings need to be carefully operated and maintained for optimum health, comfort, energy performance, and utility costs. The increasing use of Machine Learning combined with Big Data in the building services sector has shown the potential to bring energy efficiency and cost-effectiveness. Therefore, …

2022Opvoeding & OnderwijsConferentiebijdrage

Redenen voor een mismatch in trainingsbelasting tussen coaches en sporters

Kerkhoff, Marinke; Stoter, Inge; Otter, Ruby (Healthy Lifestyle, Sports And Physical Activity)

De daadwerkelijke trainingsbelasting van een sporter komt vaak niet overeen met de door de coach beoogde trainingsbelasting. Bekende oorzaken zijn een verkeerde inschatting van de belastbaarheid van de sporter en moeite met het gebruik van de RPE schaal. Op basis van recent onderzoek wordt het belang …

2022AlgemeenArtikel

The importance of satisfying children’s basic psychological needs in primary school physical education for PE-motivation, and its relations with fundamental motor and PE-related skills

de Bruijn, A.G.M.; Mombarg, R. (Sports Education & Youth Sports); Timmermans, A.C.

Background: Motivation for physical education (PE) is considered an important factor for the development of children’s physical skills during PE. According to self-determination theory, the satisfaction of the psychological needs of autonomy, relatedness, and competence is related to higher levels of …

2022AlgemeenArtikel

Environmental DNA metabarcoding reveals comparable responses to agricultural stressors on different trophic levels of a freshwater community

Kevin Beentjes (Onderzoeker); Henrik Barmentlo (Onderzoeker); Ellen Cieraad (Onderzoeker); Menno Schilthuizen (Onderzoeker); Berry van der Hoorn (Onderzoeker); Arjen Speksnijder (Lector); Krijn Trimbos (Onderzoeker)

Freshwater habitats are under stress from agricultural land use, most notably the influx of neonicotinoid pesticides and increased nutrient pressure from fertilizer. Traditional studies investigating the effects of stressors on freshwater systems are often limited to a narrow range of taxa, depending …

2021-12-06Natuur & LandbouwArtikel

A new approach for mediation analysis: Is Baron and Kenny’s method still valid

Gürbüz, Sait (Marian Van Os Centre Of Expertise Ondernemen); Bayık, Mehmet Emin

Baron and Kenny's (1986) causal steps approach has been widely used by researchers in mediation analyses. Yet, recently, some researchers have begun to argue that Baron and Kenny's approach is not an appropriate method for mediation analysis, and that contemporary or new methods that are based on bootstrapping …

2021-12-01AlgemeenArtikel

Facilitating circular site preparation; developing the instrument PrCiSi

Entrop, A.G. (Bram) (Associatelector); Hagen, L. (Lisanne) (Student); Kuiper, A.M. (Aafke)

The impact of the construction industry on the natural environment is severe, natural areas are changedinto predominantly hard solid surfaces, the energy use in the built environment is high and the industryputs huge claims on materials

2021-12-01AlgemeenArtikel

Dementie bij mensen met (zeer) ernstige verstandelijke (en meervoudige) beperkingen

Dekker, Alain D.; Wissing, Maureen B. G.; Ulgiati, Aurora M.; Bijl, Bas; van Gool, Gaby; Groen, Marieke R.; Grootendorst, Esther S.; van der Wal, Ina A.; Hobbelen, Johannes S. M. (Veroudering En Paramedische Zorg); De Deyn, Peter P.; Waninge, Aly (Participatie En Gezondheid Van Mensen Met Een Verstandelijke En Visuele Beperking)

2021-12-01AlgemeenArtikel

Wound infection following implant removal of foot, ankle, lower leg or patella; a protocol for a multicenter randomized controlled trial investigating the (cost-)effectiveness of 2 g of prophylactic cefazolin compared to placebo (WIFI-2 trial)

Sanders, Fay R.K.; Penning, Diederick; Backes, Manouk; Dingemans, Siem A.; van Dieren, Susan; Eskes, Anne M. (Lectoraat Patiënt- En Familieparticipatie In De Klinische Zorg); Goslings, J. Carel; Kloen, Peter; Mathôt, Ron A.A.; Schep, Niels W.L.; Spijkerman, Ingrid J.B.; Schepers, Tim

Background: Elective implant removal (IR) after fracture fixation is one of the most common procedures within (orthopedic) trauma surgery. The rate of surgical site infections (SSIs) in this procedure is quite high, especially below the level of the knee. Antibiotic prophylaxis is not routinely prescribed, …

2021-12AlgemeenArtikel

De missionaire mindset van pioniers binnen de Protestantse Kerk

Sake Stoppels (Lector)

De Dienstenorganisatie van de Protestantse Kerk interviewde in de eerste helft van 2021 20 aselect geworven PKN-pioniers. Via het onderzoek is een beeld ontstaan van onder meer hun theologische positie, hun inspiratiebronnen en de beleving van de (missionaire) impulsen die ze ontvangen vanuit het landelijke …

2021-11Filosofie & ReligieRapport

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