Heme is a suggested limiting factor in peroxidase production by Aspergillus spp., which are well-known suitable hosts for heterologous protein production. In this study, the role of genes coding for coproporphyrinogen III oxidase (hemF) and ferrochelatase (hemH) was analyzed by means of deletion and …

BACKGROUND: Multimorbidity, the co-occurrence of two or more chronic medical conditions within a single individual, is increasingly becoming part of daily care of general medical practice. Literature-based discovery may help to investigate the patterns of multimorbidity and to integrate medical knowledge …

This study analyses the interactions of students with the recorded lectures. We report on an analysis of students' use of recorded lectures at two Universities in the Netherlands. The data logged by the lecture capture system (LCS) is used and combined with collected survey data. We describe the process …

Recorded lectures provide an integral recording of live lectures, enabling students to review those lecture at their own pace and whenever they want. Most research into the use of recorded lectures by students has been done by using surveys or interviews. Our research combines this data with data logged …

BACKGROUND: Prednisolone and other glucocorticoids (GCs) are potent anti-inflammatory and immunosuppressive drugs. However, prolonged use at a medium or high dose is hampered by side effects of which the metabolic side effects are most evident. Relatively little is known about their effect on gene-expression …

In this article, we present CoPub 5.0, a publicly available text mining system, which uses Medline abstracts to calculate robust statistics for keyword co-occurrences. CoPub was initially developed for the analysis of microarray data, but we broadened the scope by implementing new technology and new …

What are successful companies? That question will be investigated. The determination of successful factors will be identified by explaining the successful factors of a company by the following questions: How come successful ventures are successful and non successful ventures are not? What are the most …

Doordat de bedrijfsprocessen steeds meer geautomatiseerd worden, zijn de processen complexer geworden en daarmee minder transparant. Process Mining kan hier een oplossing bieden. Process Mining is een vorm van data-analyse, gebaseerd op de procesmodellering en datamining, waarmee inzicht wordt verkregen …