Om inzicht te krijgen in spierveroudering is genexpressie gemeten in vastus lateralis biopten van jonge en oude mannen en vrouwen. We vonden dat tijdens het ouder worden bij beide geslachten dezelfde categorieën genen in spieren worden aan- en uitgeschakeld (“gereguleerd”); de mate van deze zogenaamde …

Background: Follow‑up of curatively treated primary breast cancer patients consists of surveillance and aftercare and is currently mostly the same for all patients. A more personalized approach, based on patients’ individual risk of recurrence and personal needs and preferences, may reduce patient burden …

After reopening in March 2022 Sir Adam Hotel has been dealing with a declining guest satisfaction rate of 5,6% while providing the same guest experience. Studies have shown that this is caused by the increase of negative psychological effects which are caused by COVID-19. Resulting in complained behavior …

Most aesthetic sports where judges subjectively rate performances can suffer from issues like systematic errors due to biases. Equestrian dressage is defined through the intricate interaction between horse and rider. Assessing these interactions can be particularly complex, often exceeding human processing …

When physicians and nurses are looking at the same patient, they may not see the same picture. If assuming that the clinical reasoning of both professions is alike and ignoring possible differences, aspects essential for care can be overlooked. Understanding the multifaceted concept of clinical reasoning …

Background: Roughly 200 million women become pregnant every year - most of them living in developing countries in Asia and Africa - many of these women suffer from ongoing nutritional deficiencies, contributing to the estimate of half a million maternal deaths a year. Educational programs teaching on …

Despite continuous improvement, lifelong learning, and plan-do-check-act cycles, every new day the planet is a little worse off than the day before! In the first 10 months of this year alone, an area the size of the Netherlands has been deforested and twice that area has been added to desert! Technology …

At first glance, Public Sector Innovation (PSI) Labs are gaining prominence within academic literature, the European Union (EU) and beyond. However, because of the relative newness and conceptual ambiguity of this concept, the exact contribution of these labs to theory and practice is still unclear. …

In September, the president of the Dutch central bank wrote what may have been the most remarkable letter of his career: it said that the ECB’s interest rate hikes will lead to losses for De Nederlandsche Bank (DNB) for the first time since 1932. Several countries throughout the eurozone are facing a …

BACKGROUND: Frailty is associated with COVID-19 severity in clinical settings. No general population-based studies on the association between actual frailty status and COVID-19 hospitalization are available. AIMS: To investigate the association between frailty and the risk of COVID-19 hospitalization …