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Skeletal muscle uncoupling protein-3 restores upon intervention in the pre-diabetic and diabetic state: implications for diabetes pathogenesis?

L.B. Borghouts (Lector); E. Moonen-Kornips; Schaart; M. Mensink; M.K.C. Hesselink; H.A. Keizer; Blaak; Schrauwen

Both exercise training and a lifestyle-intervention program increase UCP3 protein content inskeletal muscle of subjects with reduced glycaemic control, indicating a restoration towards normal UCP3 levels. These data support the idea that UCP3 has a role in the aetiology of type 2 diabetes mellitus

2007GezondheidArtikel

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Skeletal muscle uncoupling protein-3 restores upon intervention in the pre-diabetic and diabetic state: implications for diabetes pathogenesis?

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