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Physical fitness in children with Marfan and Loeys-Dietz syndrome

Warnink-Kavelaars, Jessica; de Koning, Lisanne E. (Urban Vitality); van der Hulst, Annelies E.; Buizer, Annemieke I.; Poissonnier, Nicole; Wijninga, Laura E.; Menke, Leonie A.; Mosquera, Laura Muiño; Rombaut, Lies; Engelbert, Raoul H.H. (Urban Vitality)

Children with Marfan (MFS) and Loeys-Dietz syndrome (LDS) report limitations in physical activities, sports, school, leisure, and work participation in daily life. This observational, cross-sectional, multicenter study explores associations between physical fitness and cardiovascular parameters, systemic …

2024-05AlgemeenArtikel

Somatic symptoms, pain, catastrophizing and the association with disability among children with heritable connective tissue disorders

de Koning, Lisanne E. (Lectoraat Fysiotherapie -Bewegen Naar Preventieve Zorg); Warnink-Kavelaars, Jessica; van Rossum, Marion A.; Bosman, Diederik; Menke, Leonie A.; Malfait, Fransiska; de Boer, Rosa; Oosterlaan, Jaap; Engelbert, Raoul H.H. (Urban Vitality); Rombaut, Lies

The aim of the present study was to investigate the nature and prevalence of nonspecific somatic symptoms, pain and catastrophizing in children with Heritable Connective Tissue Disorders (HCTD), and to determine their association with disability. This observational, multicenter study included 127 children, …

2023-07AlgemeenArtikel

Physical activity and physical fitness in children with heritable connective tissue disorders

de Koning, Lisanne (Urban Vitality); Warnink-Kavelaars, Jessica; van Rossum, Marion; Limmen, Selina; Van der Looven, Ruth; Muiño-Mosquera, Laura; van der Hulst, Annelies; Oosterlaan, Jaap; Rombaut, Lies; Engelbert, Raoul (Urban Vitality)

Objectives: Health problems in patients with heritable connective tissue disorders (HCTD) are diverse and complex and might lead to lower physical activity (PA) and physical fitness (PF). This study aimed to investigate the PA and PF of children with heritable connective tissue disorders (HCTD). Methods: …

2023AlgemeenArtikel

Heritable connective tissue disorders in childhood: Decreased health-related quality of life and mental health

Warnink-Kavelaars, Jessica; de Koning, Lisanne E. (Lectoraat Fysiotherapie -Bewegen Naar Preventieve Zorg); Rombaut, Lies; Menke, Leonie A.; Alsem, Mattijs W.; van Oers, Hedy A.; Buizer, Annemieke I.; Engelbert, Raoul H. H. (Urban Vitality); Oosterlaan, Jaap

The psychosocial consequences of growing up with Heritable Connective Tissue Disorders (HCTD) are largely unknown. We aimed to assess Health-Related Quality of Life (HRQoL) and mental health of children and adolescents with HCTD. This observational multicenter study included 126 children, aged 4–18 years, …

2022-07AlgemeenArtikel

Clinimetrics: Assessment of generalised joint hypermobility: the Beighton score

Engelbert, Raoul HH (Urban Vitality); Rombaut, Lies

2022-07AlgemeenArtikel

Heritable connective tissue disorders in childhood

Warnink-Kavelaars, Jessica; de Koning, Lisanne E (Lectoraat Fysiotherapie -Bewegen Naar Preventieve Zorg); Rombaut, Lies; Alsem, Mattijs W; Menke, Leonie A; Oosterlaan, Jaap; Buizer, Annemieke I; Engelbert, Raoul H H (Urban Vitality); On Behalf Of The Pediatric Heritable Connective Tissue Disorders Study Group

Heritable Connective Tissue Disorders (HCTD) show an overlap in the physical features that can evolve in childhood. It is unclear to what extent children with HCTD experience burden of disease. This study aims to quantify fatigue, pain, disability and general health with standardized validated questionnaires. …

2021-05-28AlgemeenArtikel

Psychosocial- and physical functioning in hypermobile Ehlers-Danlos Syndrome: a 5-year follow-up study

de Vries, Janneke (Lectoraat Fysiotherapie -Bewegen Naar Preventieve Zorg); Rombaut, Lies; De Wandele, Inge; Scheper, Mark; Malfait, Franciska; Engelbert, Raoul; Calders, Patrick

2018-09-26AlgemeenConferentiebijdrage

Measurement Properties of Clinical Assessment Methods for Classifying generalized joint hypermobility-A systematic review

Juul-Kristensen, Birgit; Schmedling, Karoline; Rombaut, Lies; Lund, Hans; Engelbert, Raoul H.H. (Faculteit Gezondheid)

The purpose was to perform a systematic review of clinical assessment methods for classifying Generalized Joint Hypermobility (GJH), evaluate their clinimetric properties, and perform the best evidence synthesis of these methods. Four test assessment methods (Beighton Score [BS], Carter and Wilkinson, …

2017-03AlgemeenArtikel

Disability in adolescents and adults diagnosed with hypermobility-related Disorders: a meta-analysis

Scheper, Mark C.; Juul-Kristensen, Birgit; Rombaut, Lies; Rameckers, Eugene A.; Verbunt, Jeanine; Engelbert, Raoul H. (Faculteit Gezondheid)

OBJECTIVE: To (1) establish the association of the most common reported symptoms on disability; and (2) study the effectiveness of treatment on disability in patients with Ehlers-Danlos syndrome-hypermobility type (EDS-HT)/hypermobility syndrome (HMS). DATA SOURCES: An electronic search (Medical Subject …

2016-12AlgemeenArtikel

The association between muscle strength and activity limitations in patients with the hypermobility type of Ehlers-Danlos syndrome: the impact of proprioception

Scheper, Mark; Rombaut, Lies; de Vries, Janneke; De Wandele, Inge; van der Esch, Martin (Faculteit Gezondheid); Visser, Bart (Faculteit Gezondheid); Malfait, Franciska; Calders, Patrick; Engelbert, Raoul (Faculteit Gezondheid)

PURPOSE: The patients diagnosed with Ehlers-Danlos Syndrome Hypermobility Type (EDS-HT) are characterized by pain, proprioceptive inacuity, muscle weakness, potentially leading to activity limitations. In EDS-HT, a direct relationship between muscle strength, proprioception and activity limitations has …

2016-06-24AlgemeenArtikel

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