BACKGROUND: Frailty is often associated with multimorbidity and disability. OBJECTIVES: We investigated heterogeneity in the frail older population by characterizing five subpopulations according to quantitative biological markers, multimorbidity and disability, and examined their association with mortality …

BACKGROUND: Multimorbidity, the co-occurrence of two or more chronic medical conditions within a single individual, is increasingly becoming part of daily care of general medical practice. Literature-based discovery may help to investigate the patterns of multimorbidity and to integrate medical knowledge …

Objective: Multimorbidity is known for its negative effects on health related functioning. It remains unclear if these effects are stable over time. The aim was to investigate if the relation between single morbidity/multimorbidity and health related functioning is temporary or persistent. Methods: Data …

BACKGROUND: Multimorbidity has been suggested to be associated with a variety of negative health-related outcomes. The present study was designed to evaluate the association between multimorbidity and subjective memory complaints. METHODS: This cross-sectional study was based on data obtained from a …

OBJECTIVE: The prevalence of multimorbidity has risen considerably because of the increase in longevity and the rapidly growing number of older individuals. Today, only little is known about the influence of multimorbidity on cognition in a normal healthy aging population. The primary aim of the present …

Doel Multimorbiditeit komt veel voor in de huisartsenpraktijk. Men associeert specifieke ziekten vaak met cognitieve achteruitgang, maar er is weinig bekend over de invloed van multimorbiditeit op het cognitief functioneren. Methode We selecteerden personen tussen de 24 en 81 jaar (n = 1763) uit het …

Contexte La multimorbidité est définie par la coexistence d’au moins deux pathologies chroniques. De précédents travaux ont montré un retentissement négatif de la multimorbidité sur la qualité de vie mentale ou physique1. En soins primaires, la prévalence d’un état dépressif caractérisé est 3 fois plus …