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Zocht je misschien: cassave, cascade?

Prednisolone-induced beta cell dysfunction is associated with impaired endoplasmic reticulum homeostasis in INS-1E cells

Linssen, Margot M L; van Raalte, Daniel H; Toonen, Erik J M; Alkema, Wynand; van der Zon, Gerard C; Dokter, Wim H; Diamant, Michaela; Guigas, Bruno; Ouwens, D Margriet

Glucocorticoids (GCs), such as prednisolone (PRED), are widely prescribed anti-inflammatory drugs, but their use may induce glucose intolerance and diabetes. GC-induced beta cell dysfunction contributes to these diabetogenic effects through mechanisms that remain to be elucidated. In this study, we hypothesized …

2011-11-01AlgemeenArtikel

Transcriptional profiling reveals complex regulation of the monocyte IL-1 beta system by IL-13

Scotton, Chris J; Martinez, Fernando O; Smelt, Maaike J; Sironi, Marina; Locati, Massimo; Mantovani, Alberto; Sozzani, Silvano

IL-4 and IL-13 are prototypic Th2 cytokines that generate an “alternatively activated” phenotype in macrophages. We used high-density oligonucleotide microarrays to investigate the transcriptional profile induced in human monocytes by IL-13. After 8-h stimulation with IL-13, 142 genes were regulated …

2005-01-15AlgemeenArtikel

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Prednisolone-induced beta cell dysfunction is associated with impaired endoplasmic reticulum homeostasis in INS-1E cells

Transcriptional profiling reveals complex regulation of the monocyte IL-1 beta system by IL-13

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