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Endotoxin method for pharmaceutical products according to “Good Manufacturing Practices” (GMP) rules

Iris Gülcher (Student)

Over the period February 2023 to July 2023, the aim was to develop a method for the determination of endotoxin in pharmaceutical products according to GMP rules. To bring this research to a successful conclusion, the intention was to demonstrate endotoxins in pharmaceutical products using the Kinetic …

2024-05-06Gezondheid; …Bachelor

Use of Aureobasidium in a sustainable economy

Rensink, (Stephanie) (Onderzoeker); Sailer, (Michael) (Onderzoeker); Wösten, A.B. (Han) (Extern); Struck, (Christian) (Lector); Nieuwenhuijzen, (Elke) van (Onderzoeker)

Abstract Aureobasidium is omnipresent and can be isolated from air, water bodies, soil, wood, and other plant materials, as well as inorganic materials such as rocks and marble. A total of 32 species of this fungal genus have been identified at the level of DNA, of which Aureobasidium pullulans is best …

2024-02-13AlgemeenArtikel

ALIFe lezing: Microbiële ecosystemen - Toekomstige werkpaarden voor energie, gezondheid en landbouw

Nap, Jan Peter

ALIFE Lezing Instituut voor Life Science & Technology

2023-10-04Gezondheid; …Conferentiebijdrage

Understanding the effect of an educational intervention to optimize HIV testing strategies in primary care in Amsterdam – results of a mixed-methods study

Bogers, Saskia; Nieuwkerk, Pythia; van Dijk, Nynke; Schim van der Loeff, Maarten; Geerlings, Suzanne; van Bergen, Jan

Background: In the Netherlands, general practitioners (GPs) play a key role in provider-initiated HIV testing, but opportunities for timely diagnosis are regularly missed. We implemented an educational intervention to improve HIV testing by GPs from 2015 to 2020, and observed a 7% increase in testing …

2023-09-30AlgemeenArtikel

Dutch Delight – health opportunities of tulip pigments

Smelt, Maaike

2022-06-21TechniekConferentiebijdrage

Temperature and nutrient limitations decrease transfer of conjugative IncP-1 plasmid pKJK5 to wild Escherichia coli strains

Pallares-Vega, R.; Macedo, G.; Brouwer, M.S.M.; Hernandez-Leal, L.; Maas, P.M.F. van der (Lector); Loosdrecht, M.C.M. van; Weissbrodt, D.G.; Heederik, D.; Mevius, D.; Schmitt, H.

Plasmid-mediated dissemination of antibiotic resistance among fecal Enterobacteriaceae in natural ecosystems may contribute to the persistence of antibiotic resistance genes in anthropogenically impacted environments. Plasmid transfer frequencies measured under laboratory conditions might lead to overestimation …

2021-07-19TechniekArtikel

Sputum Proteome Signatures of Mechanically Ventilated Intensive Care Unit Patients Distinguish Samples with or without Anti-pneumococcal Activity

Seinen, Jolien; Engelke, Rudolf; Abdullah, Mohammed R; Voß, Franziska; Michalik, Stephan; Dhople, Vishnu M; Dieperink, Willem; de Smet, Anne Marie G A; Völker, Uwe; van Dijl, Jan Maarten; Schmidt, Frank; Hammerschmidt, Sven

Respiratory pathogens like Streptococcus pneumoniae can cause severe pneumonia. Nonetheless, mechanically ventilated intensive care patients, who have a high risk of contracting pneumonia, rarely develop pneumococcal pneumonia. Mechanically ventilated patients are at risk of contracting pneumonia. Therefore, …

2021-04-27AlgemeenArtikel

Microbiota in Dung and Milk Differ Between Organic and Conventional Dairy Farms

Sophia Gomes (Onderzoeker); Peter van Bodegom (Onderzoeker); Maaike van Agtmaal (Onderzoeker); Nadejda Soudzilovskaia (Onderzoeker); Monique Bestman (Onderzoeker); Elza Duijm (Onderzoeker); Arjen Speksnijder (Onderzoeker); Nick van Eekeren (Onderzoeker)

Organic farming is increasingly promoted as a means to reduce the environmental impact of artificial fertilizers, pesticides, herbicides, and antibiotics in conventional dairy systems. These factors potentially affect the microbial communities of the production stages (soil, silage, dung, and milk) of …

2020-07-28Natuur & LandbouwArtikel

Revealing new leads for the impact of galacto-oligosaccharides on gut commensals and gut health benefits through text mining

Sijbers, A.M.; Schoemaker, R.J.W.; Nauta, A.; Alkema, Wynand (Data Science For Life Science & Health)

2020-04-17AlgemeenArtikel

Thauera aminoaromatica MZ1T Identified as a Polyhydroxyalkanoate-Producing Bacterium within a Mixed Microbial Consortium

Colpa, Dana; Zhou, Wen; Wempe, Jan Pier; Tamis, Jelmer; Krooneman, Janneke (Bioconversion And Fermentation Technology); Euverink, Gerrit Jan Willem; Stuart, Marc C. A.

Polyhydroxyalkanoates (PHAs) form a highly promising class of bioplastics for the transition from fossil fuel-based plastics to bio-renewable and biodegradable plastics. Mixed microbial consortia (MMC) are known to be able to produce PHAs from organic waste streams. Knowledge of key-microbes and their …

2020-02-21AlgemeenArtikel

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