Owing to the non-toxic, nonimmunogenic effects and high affinity to specific molecules, some single-stranded oligonucleotides, namely aptamers, can be exploited in biochemical applications to deliver bioactive elements and interact with the desired targets. Among many identified aptamers, D#7 was utilized …

The long spined sea urchin Diadema antillarum was an abundant grazer on Caribbean coral reefs, until 1983–1984, when densities were reduced by ∼98% during a region wide die-off. Since then, there has been very little natural recovery of the species and interest is growing in applying aquaculture as a …

The dairy goat sector in Norway is confronted to a certain problem since many years, the increase of the cells in goat milk. This cell issue seem to become a big problem for the goat farmers because the somatic cell count and the bacteria count are the base of the payment grid. Other studies in the world …

Non-small cell lung cancer (NSCLC) occurs in approximately 80-85% of all lung cancer patients and has a 5-year overall survival (OS) of only 15-20%. In this study, 29 NSCLC patients received neoadjuvant treatment with Chemoradiotherapy, Nivolumab, and Ipilimumab. This study aimed to investigate the effects …

This literature review will focus on how CRISPR/Cas can be used in curing diabetes. CRISPR is a newly discovered genetical engineering tool that was first found in bacteria and it has an important immune function, protecting them from viral infections by cutting the viral DNA, thereby disabling it. Researchers …

Psoriasis (Pso) is a chronic inflammatory skin disease, and up to 30% of Pso patients develop psoriatic arthritis (PsA), which can lead to irreversible joint damage. Early detection of PsA in Pso patients is crucial for timely treatment but difficult for dermatologists to implement. We, therefore, aimed …

IL22 is an important cytokine involved in the intestinal defense mechanisms against microbiome. By using ileum-derived organoids, we show that the expression of anti-microbial peptides (AMPs) and anti-viral peptides (AVPs) can be induced by IL22. In addition, we identified a bacterial and a viral route, …

Cutaneous melanoma is a type of skin cancer that develops from benign melanocytes to one of the most aggressive types of skin tumors in human. In cutaneous melanoma progression, the metastasis phase is the most challenging phase to treat. To enable earlier treatment options, a better understanding of …

From the article: "Scope: During food processing, the Maillard reaction ( М R) may occur, resulting in the formation of glycated proteins. Glycated proteins are of particular importance in food allergies because glycation may influence interactions with the immune system. This study compared native …

From PLoS website: In general, dietary antigens are tolerated by the gut associated immune system. Impairment of this so-called oral tolerance is a serious health risk. We have previously shown that activation of the ligand-dependent transcription factor aryl hydrocarbon receptor (AhR) by the environmental …