Alzheimer's disease (AD) is the common neurodegenerative disorder and the most frequent cause of dementia. The disease accounts around 80% of all dementia diagnoses. The main reason of developing AD is amyloid cascade which starts from missense mutations in APP (amyloid precursor protein), Rho-associated …

In het Catharina Ziekenhuis Eindhoven op de afdeling Nucleaire Geneeskunde wordt er met F18 Flutemetamol β-amyloid PET-CT onderzoek gedaan naar dementiële beelden waaronder de ziekte van Alzheimer en is er behoefte aan een geactualiseerd protocol. Het F18 Flutemetamol β-amyloid PET-CT protocol moet …

Alzheimer.s disease (AD) is a neurodegenerative disease. The disease is characterized by the presence of neuropathology hallmarks such as: senile plaques, neurofibrillary tangles and the loss of synapses and neurons in the brain. The senile plaques are mainly composed of amyloid fibrils of the protein …